Hachemi M, Oukil N, Touarigt F Z, Hasbellaoui M
University of Medicine of Algiers I, Chu Bab El Oued, Algiers, Algeria.
University of Medicine of Algiers I, Chu Bab El Oued, Algiers, Algeria.
Int J Surg Case Rep. 2024 Oct;123:110153. doi: 10.1016/j.ijscr.2024.110153. Epub 2024 Aug 10.
Chondroosseous respiratory adenomatous epithelial hamartoma (COREAH) is a rare benign lesion of the nose and sinuses, with some cases reported in the literature.
We present here a case of COREAH, in a woman whose clinical examination finds a polypoid mass in the left nasal cavity. Computed tomography (CT) and magnetic resonance imaging (MRI) confirmed the presence of a large mass in the anterior nasal cavity extended to the cranial cavity through the screened blade on the right side. The mass was completely resected by endoscopy. Histological examination confirmed the nature of the mass as COREAH. A hamartoma can be considered a proliferation of endogenous cells or tissues at this anatomical site.
Several hamartomatous lesions have been recognized in the sinonasal region. The majority are mesenchymal, most often vascular lesions. Pure chondromatous hamartomas of the nasal cavity, although rare, also occur.
COREAH is a benign hamartomatous proliferation of the respiratory epithelium, submucosal glands and chondroosseous mesenchyma. Differential clinical diagnoses include benign and malignant tumors of the nasal cavity and sinuses. Properly recognizing this lesion as radiologically benign is essential to avoid radical surgery.
软骨骨性呼吸性腺瘤样上皮错构瘤（COREAH）是一种罕见的鼻及鼻窦良性病变，文献中有部分病例报道。
我们在此呈现一例COREAH病例，患者为一名女性，临床检查发现左侧鼻腔有一个息肉样肿物。计算机断层扫描（CT）和磁共振成像（MRI）证实鼻腔前部有一个大肿物，通过右侧筛板延伸至颅腔。该肿物经内镜完全切除。组织学检查证实肿物性质为COREAH。错构瘤可被视为该解剖部位内源性细胞或组织的增生。
鼻窦区域已识别出多种错构瘤性病变。大多数为间叶性病变，最常见的是血管病变。鼻腔的纯软骨瘤样错构瘤虽然罕见，但也会发生。
COREAH是呼吸上皮、黏膜下腺体和软骨骨性间叶组织的良性错构瘤性增生。临床鉴别诊断包括鼻腔和鼻窦的良性及恶性肿瘤。正确认识该病变在影像学上为良性对于避免根治性手术至关重要。
