Bhardwaj Ashok Kumar, Kumar Dinesh, Raina Sunil Kumar, Bansal Pradeep, Bhushan Satya, Chander Vishav
Department of Community Medicine, Dr. Rajendra Prasad Government Medical College, Kangra, Himachal Pradesh 176001, India.
Department of Biochemistry, Dr. Rajendra Prasad Government Medical College, Kangra, Himachal Pradesh 176001, India.
Biochem Res Int. 2013;2013:696845. doi: 10.1155/2013/696845. Epub 2013 Dec 22.
Context. Evident change in nutrition and lifestyle among individuals of urban and rural areas raises suspicion for similar change in tribal area population of India. Aim. To study the biochemical risk factor for CVDs in rural and tribal population of Sub-Himalayan state of India. Settings and Design. Cross-sectional study in rural (low altitude) and tribal (high altitude) area of Himachal Pradesh, India. Methodology. Blood lipid profile using standard laboratory methods. Statistical Analysis. Chi-square test and multiple linear regression analysis. Results. Total of 900 individuals were studied in both areas. As per Asian criteria, obesity (BMI 27.5-30.0 kg/m(2)) was observed to be significantly high (P = 0.00) as 13.7% in tribal area as compared to 5.5% in rural area. Normal level of TC (<200 mg/dL) and LDL (<130 mg/dL) was observed in the majority of the population of both areas, whereas, at risk level of HDL (<40 mg/dL) was present in half of the population of both rural and tribal areas. The prevalence of borderline to high level of TGs was observed to be 60.2% and 55.2% in rural and tribal (P = 0.10) area, respectively. Conclusion. Prevalent abnormal lipid profile in tribal area demands establishment of an effective surveillance system for development of chronic diseases.
背景。印度城乡地区人群的营养和生活方式发生了明显变化，这引发了人们对印度部落地区人群是否也有类似变化的怀疑。目的。研究印度喜马拉雅邦农村和部落人群心血管疾病的生化风险因素。研究地点和设计。在印度喜马偕尔邦的农村（低海拔）和部落（高海拔）地区进行横断面研究。方法。采用标准实验室方法检测血脂谱。统计分析。卡方检验和多元线性回归分析。结果。两个地区共研究了900人。根据亚洲标准，肥胖（BMI 27.5 - 30.0 kg/m²）在部落地区的发生率显著较高（P = 0.00），为13.7%，而农村地区为5.5%。两个地区的大多数人群的总胆固醇（TC）水平正常（<200 mg/dL）和低密度脂蛋白（LDL）水平正常（<130 mg/dL），然而，农村和部落地区各有一半人口的高密度脂蛋白（HDL）处于风险水平（<40 mg/dL）。农村和部落地区甘油三酯（TG）处于临界高水平的患病率分别为60.2%和55.2%（P = 0.10）。结论。部落地区普遍存在的异常血脂谱情况要求建立一个有效的监测系统，以应对慢性病的发展。
