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欧洲癌症研究与治疗组织生活质量问卷QLQ-C30的欧洲参考值:一项德国调查结果及六项欧洲普通人群规范研究的汇总分析

European reference values for the quality of life questionnaire EORTC QLQ-C30: Results of a German investigation and a summarizing analysis of six European general population normative studies.

作者信息

Hinz Andreas, Singer Susanne, Brähler Elmar

机构信息

Department of Medical Psychology and Medical Sociology, University of Leipzig , Leipzig , Germany.

出版信息

Acta Oncol. 2014 Jul;53(7):958-65. doi: 10.3109/0284186X.2013.879998. Epub 2014 Jan 23.

Abstract

BACKGROUND

The aims of this study are to present the results of a new general population normative study of the quality of life questionnaire EORTC QLQ-C30 and to give European reference values averaged across six studies.

METHODS

The empirical study was based on a representative sample of the German adult population (N = 2448). The subjects were asked to fill in several questionnaires, one of them being the EORTC QLQ-C30.

RESULTS

EORTC QLQ-C30 mean scores of this sample indicated slightly better quality of life (QoL) than in previous European studies. QoL decreased with age, but there were only small gender differences. The mean scores were compared with the age and gender adjusted scores of five other European normative studies from Sweden, the Netherlands, Norway, and Germany (N between 1731 and 4910). Finally, the data of these five studies and the new study were combined to arrive at averaged European normative values for the scales and the symptom items of the questionnaire.

CONCLUSION

The reference values of the scales pooled across six European studies (N = 16 151) can be used as general population references for QoL scores of cancer patients.

摘要

背景

本研究旨在呈现一项关于生活质量问卷EORTC QLQ - C30的新的普通人群规范性研究结果,并给出六项研究的欧洲平均参考值。

方法

实证研究基于德国成年人群的代表性样本(N = 2448)。受试者被要求填写几份问卷,其中一份是EORTC QLQ - C30。

结果

该样本的EORTC QLQ - C30平均得分表明生活质量(QoL)略高于以往欧洲研究。生活质量随年龄下降,但性别差异较小。将平均得分与来自瑞典、荷兰、挪威和德国的其他五项欧洲规范性研究(N在1731至4910之间)的年龄和性别调整得分进行比较。最后,将这五项研究的数据与新研究的数据相结合,得出问卷各量表和症状项目的欧洲平均规范性值。

结论

六项欧洲研究(N = 16151)汇总的量表参考值可作为癌症患者生活质量得分的普通人群参考值。

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