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A群链球菌异源M蛋白编码转录本中存在的一个高度保守区域。

A highly conserved region present in transcripts encoding heterologous M proteins of group A streptococci.

作者信息

Hollingshead S K, Fischetti V A, Scott J R

机构信息

Department of Microbiology and Immunology, Emory University Health Sciences Center, Atlanta, Georgia 30322.

出版信息

Infect Immun. 1987 Dec;55(12):3237-9. doi: 10.1128/iai.55.12.3237-3239.1987.

DOI:10.1128/iai.55.12.3237-3239.1987
PMID:2445686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC260060/
Abstract

In group A streptococcal strains of 10 different serotypes, the sequence previously identified as homologous to the structural gene for type 6 M protein (emm6) was found to be transcribed. The conserved sequence, which shows greater than 95% homology among heterologous M proteins, was identified as the 3' third of the gene.

摘要

在10种不同血清型的A组链球菌菌株中，发现先前鉴定为与6型M蛋白（emm6）结构基因同源的序列被转录。该保守序列在异源M蛋白之间显示出大于95%的同源性，被鉴定为该基因的3'末端三分之一。

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A highly conserved region present in transcripts encoding heterologous M proteins of group A streptococci.A群链球菌异源M蛋白编码转录本中存在的一个高度保守区域。
Infect Immun. 1987 Dec;55(12):3237-9. doi: 10.1128/iai.55.12.3237-3239.1987.
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本文引用的文献

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Antigenicity of the M proteins of group A hemolytic streptococci. IV. Cross-reactivity between serotypes.A 组溶血性链球菌 M 蛋白的抗原性。IV. 血清型之间的交叉反应性。
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Relationship of M protein genes in group A streptococci.A组链球菌中M蛋白基因的关系
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Conversion of an M- group A streptococcus to M+ by transfer of a plasmid containing an M6 gene.通过转移含有M6基因的质粒将M群A组链球菌转化为M+型。
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