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视网膜色素变性患者的视觉训练与情绪状态

Visual training and emotional state of people with retinitis pigmentosa.

作者信息

Chacón-López Helena, Pelayo Francisco J, López-Justicia María D, Morillas Christian A, Ureña Raquel, Chacón-Medina Antonio, Pino Begoña

机构信息

Department of Developmental and Educational Psychology, Faculty of Educational Sciences, University of Granada, Campus Universitario de La Cartuja, s/n, 18071-Granada, Spain.

出版信息

J Rehabil Res Dev. 2013;50(8):1157-68. doi: 10.1682/JRRD.2012.06.0113.

DOI:10.1682/JRRD.2012.06.0113
PMID:24458902
Abstract

The purpose of the study was to improve the visual functioning of people with restriction in contrast sensitivity (CS), such as retinitis pigmentosa (RP), by means of a visual training program. Twenty-six volunteers with RP participated, distributed in two groups: 15 who made up the experimental group (who received the training program) and 11 who participated as a control group (without training). Participants were evaluated before beginning training, on completion, and 3 mo following completion for CS with the Pelli-Robson Contrast Sensitivity (P&R) test, visual functioning with the Visual Function Questionnaire (VFQ), and in emotional state with the Beck Depression Inventory (BDI). The training program is based on software that generates luminous stimuli of varying duration and intensity and registers the stimuli perceived by the subject. The outcomes showed significant differences posttraining in the experimental group in depression (F1,14 = 5.42; p < 0.04), VFQ (Z = -2.27; p < 0.02), and P&R in the right eye (Z = -1.99; p < 0.046) and left eye (Z = -2.30; p < 0.02) but not in binocular (Z = -0.96; p < 0.34). The outcomes showed that the experimental group made significant progress in all variables and these effects remained after 3 mo, which suggests that the program could be a helpful addition to RP rehabilitation and help mitigate the damage.

摘要

本研究的目的是通过视觉训练计划,改善对比敏感度(CS)受限人群(如视网膜色素变性(RP)患者)的视觉功能。26名RP志愿者参与了研究,分为两组:15名组成实验组(接受训练计划),11名作为对照组(不接受训练)。在训练开始前、结束时以及结束后3个月,使用佩利-罗布森对比敏感度(P&R)测试评估参与者的CS,使用视觉功能问卷(VFQ)评估视觉功能,并使用贝克抑郁量表(BDI)评估情绪状态。训练计划基于一款软件,该软件可生成持续时间和强度各异的光刺激,并记录受试者感知到的刺激。结果显示,训练后实验组在抑郁(F1,14 = 5.42;p < 0.04)、VFQ(Z = -2.27;p < 0.02)以及右眼(Z = -1.99;p < 0.046)和左眼(Z = -2.30;p < 0.02)的P&R方面存在显著差异,但双眼(Z = -0.96;p < 0.34)无差异。结果表明,实验组在所有变量上都取得了显著进展,且这些效果在3个月后依然存在,这表明该计划可能是RP康复的有益补充,有助于减轻损伤。

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