Recco Lucas C, Tokarev Ihor, Minko Sergiy, Pedrosa Valber A
Institute of Biosciences, Department of Chemistry and Biochemistry, UNESP, Botucatu, SP (Brazil), Fax: (+55) 14-38800576.
Chemistry. 2014 Jan 27;20(5):1226-30. doi: 10.1002/chem.201304148.
Herein we demonstrate a plasmonic nanobiosensor that explores chain reaction amplification mechanisms to transduce chemical signals released in biocatalytic reactions, turning optical signals into a visual spectral range. The sensor has a very simple design: gold nanoparticles resting in the surface of a grafted P2VP film. Changes in the gold nanoparticles' position causes changes in the plasmon coupling mode. This is detected by means of a maximum absorbance shift.
在此，我们展示了一种等离子体纳米生物传感器，该传感器探索链式反应放大机制，以转换生物催化反应中释放的化学信号，将光信号转换为可见光谱范围。该传感器设计非常简单：金纳米颗粒位于接枝的聚2-乙烯基吡啶（P2VP）薄膜表面。金纳米颗粒位置的变化会导致等离子体耦合模式的变化。这通过最大吸光度位移来检测。
