Burke D S, Nisalak A, Gentry M K
Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
J Med Virol. 1987 Oct;23(2):165-73. doi: 10.1002/jmv.1890230209.
Human flavivirus group-reactive, dengue complex-reactive, and encephalitis virus complex-reactive antibodies were detected using epitope-blocking immunoassays in which the binding of selected mouse monoclonal antibodies to flavivirus antigens was blocked by human serum. When late (greater than 6 months after illness) convalescent sera were tested, the epitope-blocking immunoassays were superior to the hemagglutination inhibition test and comparable to the plaque reduction neutralization for identifying subjects immune to dengue, to Japanese encephalitis, or both viruses.
