Seo Jang Won, Park Tae Jin
Department of Internal Medicine, Hallym University College of Medicine, Chunchon, Korea.
Electrolyte Blood Press. 2006 Nov;4(2):72-6. doi: 10.5049/EBP.2006.4.2.72.
Rapid correction of hyponatremia is frequently associated with increased morbidity and mortality. Therefore, it is important to estimate the proper volume and type of infusate required to increase the serum sodium concentration predictably. The major common management errors during the treatment of hyponatremia are inadequate investigation, treatment with fluid restriction for diuretic-induced hyponatremia and treatment with fluid restriction plus intravenous isotonic saline simultaneously. We present two cases of management errors. One is about the problem of rapid correction of hyponatremia in a patient with sepsis and acute renal failure during continuous renal replacement therapy in the intensive care unit. The other is the case of hypothyroidism in which hyponatremia was aggravated by intravenous infusion of dextrose water and isotonic saline infusion was erroneously used to increase serum sodium concentration.
低钠血症的快速纠正常与发病率和死亡率增加相关。因此,重要的是要预估可预测地提高血清钠浓度所需的输注液的合适容量和类型。低钠血症治疗期间主要的常见管理错误包括检查不充分、对利尿剂所致低钠血症采用限液治疗以及同时采用限液加静脉输注等渗盐水治疗。我们呈现两例管理错误的病例。一例是关于重症监护病房中一名脓毒症和急性肾衰竭患者在持续肾脏替代治疗期间低钠血症的快速纠正问题。另一例是甲状腺功能减退症,其中静脉输注葡萄糖水使低钠血症加重,并且错误地使用等渗盐水输注来提高血清钠浓度。