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中年女性的就业状况、抑郁症状与腰围变化:妇女健康全国性研究(SWAN)。

Employment status, depressive symptoms, and waist circumference change in midlife women: the Study of Women's Health Across the Nation (SWAN).

机构信息

Department of Preventive Medicine, Rush University Medical Center, Chicago, IL; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL.

Department of Preventive Medicine, Rush University Medical Center, Chicago, IL.

出版信息

Ann Epidemiol. 2014 Mar;24(3):187-92. doi: 10.1016/j.annepidem.2013.12.005. Epub 2013 Dec 28.

Abstract

PURPOSE

Changes in employment status have shown inconsistent associations with adiposity. This study tested whether the presence of elevated depressive symptoms explains variability in the time-varying association between employment status and central adiposity.

METHOD

Employment status, depressive symptoms, and waist circumference (WC) were assessed annually over 10 years in a multiethnic sample of 3220 midlife women enrolled in the Study of Women's Health Across the Nation. Linear mixed-effects models tested time-varying associations of employment status, depressive symptoms, and their interaction with WC.

RESULTS

WC increases were greatest during the years of combined nonemployment and elevated depressive symptoms (1.00 cm/y) and lowest in the years of full-time employment and elevated depressive symptoms (0.25 cm/y), compared with the years of full-time employment and nonelevated depressive symptoms (0.51 cm/y). Employment status was unrelated to WC in years without elevated depressive symptoms. The pattern of results was unchanged when analyses were restricted to preretirement observations and did not vary according to WC at baseline or ethnicity/race.

CONCLUSIONS

Identifying and managing depressive symptoms in midlife women who are not working may help prevent increases in central adiposity.

摘要

目的

就业状态的变化与肥胖之间的关系并不一致。本研究旨在检验抑郁症状的存在是否可以解释就业状态与中心性肥胖之间时变关联的可变性。

方法

在一项参加妇女健康全国研究的多民族中年女性样本中,每年评估一次就业状态、抑郁症状和腰围(WC),共 10 年。线性混合效应模型测试了就业状态、抑郁症状及其与 WC 的交互作用的时变关联。

结果

与无抑郁症状且全职工作的年份(0.51cm/y)相比,同时处于非就业和抑郁症状升高状态的年份(1.00cm/y)WC 增加最大,而同时处于全职工作和抑郁症状升高状态的年份(0.25cm/y)WC 增加最小。在无抑郁症状的年份,就业状态与 WC 无关。当分析仅限于退休前的观察结果时,结果模式保持不变,且与基线时的 WC 或族裔/种族无关。

结论

识别和管理非工作中年女性的抑郁症状可能有助于预防中心性肥胖的增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d676/3952632/a53fcb597be6/nihms552792f1.jpg

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