Center for Medical, Agricultural and Veterinary Entomology, USDA-ARS , 1700 SW 23 Drive, Gainesville, Florida 32604, United States.
J Nat Prod. 2014 Feb 28;77(2):402-5. doi: 10.1021/np400807v. Epub 2014 Jan 27.
Methyl farnesoate, [methyl (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoate (1)] has not been thought be present in the hemolymph of insects, although it is the immediate biosynthetic precursor of the circulating insect hormone juvenile hormone III (methyl (2E,6E)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate) (2). Compound 1 was identified from the hemolymph obtained from five orders of insects. Identification of 1 from the American bird grasshopper was facilitated using both electron impact and chemical-ionization GC-MS, GC-FTIR, and 2D NMR techniques. The identifications from other insects were made using GC-MS, and the amounts of all were quantified using LIM-CI-GC-MS. The ratios of 1 and 2 varied in these insects during different developmental stages. The present results underscore the need for further studies on methyl farnesoate (1) as a circulating hormone in insects.
法呢酯，[（2E，6E）-3，7，11-三甲基十二-2，6，10-三烯酸甲酯（1）]，尽管它是循环昆虫激素保幼激素 III（（2E，6E）-10，11-环氧-3，7，11-三甲基-2，6-十二碳二烯酸甲酯）的直接生物合成前体，但人们一直认为它不存在于昆虫的血淋巴中。1 从来自五个昆虫目的血淋巴中鉴定出来。使用电子冲击和化学电离 GC-MS、GC-FTIR 和 2D NMR 技术，从美洲鸟蝗中鉴定出 1 得到了促进。从其他昆虫中鉴定出来的则使用了 GC-MS，所有物质的含量均使用 LIM-CI-GC-MS 进行定量。在不同的发育阶段，这些昆虫中 1 和 2 的比例有所不同。目前的结果强调了需要进一步研究法呢酯（1）作为昆虫中循环激素的作用。
