Department of Chemistry and Biochemistry, University of Arlington, 700 Planetarium Place, Arlington, TX 76019, United States.
Department of Chemistry and Biochemistry, University of Arlington, 700 Planetarium Place, Arlington, TX 76019, United States.
J Chromatogr A. 2022 Aug 2;1676:463255. doi: 10.1016/j.chroma.2022.463255. Epub 2022 Jun 15.
Gas chromatography has always been a simple and widely used technique for the separation of volatile compounds and their quantitation. However, the common detectors used with this technique are mostly universal and do not provide any specific qualitative information. There have been some attempts to combine the separation power of GC with the qualitative capabilities of "high-information" spectroscopic techniques including infrared spectroscopy, nuclear magnetic resonance spectroscopy, molecular rotational resonance spectroscopy, and vacuum ultraviolet spectroscopy. Some of these hyphenations have proven to be quite successful while others were less so. The history of such attempts, up to the most recent studies in this area, are discussed. Most recently, the hyphenation of GC with molecular rotational resonance spectroscopy which provides promising results and is a newly developed technique is reviewed and compared to previous high-information spectroscopic detection approaches. The history, description and features of each method along with their applications and challenges are discussed.
气相色谱法一直是一种简单且广泛应用于分离挥发性化合物及其定量的技术。然而，与该技术一起使用的常见检测器大多是通用的，不能提供任何特定的定性信息。已经有一些尝试将 GC 的分离能力与包括红外光谱、核磁共振光谱、分子旋转共振光谱和真空紫外光谱在内的“高信息量”光谱技术的定性能力相结合。其中一些组合已经被证明非常成功，而其他则不然。讨论了这些尝试的历史，直到该领域的最新研究。最近，综述了与分子旋转共振光谱相结合的 GC 技术，该技术提供了有前途的结果，是一种新开发的技术，并与以前的高信息量光谱检测方法进行了比较。讨论了每种方法的历史、描述和特点及其应用和挑战。
