Dallas, Texas From the Department of Plastic Surgery, University of Texas Southwestern Medical Center.
Plast Reconstr Surg. 2014 Feb;133(2):127e-132e. doi: 10.1097/PRS.0b013e3182a4c282.
Soft-tissue augmentation has become an increasingly popular option for facial rejuvenation. Hyaluronic acid fillers are part of the most rapidly expanding segment of this market, largely because of their safe drug profile and temporary nature. Despite their good safety profile, they can and do have complications ranging from superficial placement, uneven placement, granulomatous reactions, and skin necrosis. This article reviews the on- and off-label uses of hyaluronidase and presents several clinical algorithms detailing the effective and safe use of hyaluronidase to manage complications secondary to hyaluronic acid fillers.
软组织填充已成为面部年轻化的一种越来越受欢迎的选择。透明质酸填充剂是该市场增长最快的部分之一，主要是因为它们具有安全的药物特性和暂时性。尽管它们的安全性良好，但它们确实会出现并发症，包括浅层放置、不均匀放置、肉芽肿反应和皮肤坏死。本文回顾了透明质酸酶的标签内和标签外用途，并提出了几种临床算法，详细说明了透明质酸酶的有效和安全使用，以管理透明质酸填充剂引起的并发症。
