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沙门氏菌属中的O抗原变异：三株菌株的rfb基因簇

O-antigen variation in Salmonella spp.: rfb gene clusters of three strains.

作者信息

Verma N K, Quigley N B, Reeves P R

机构信息

Department of Microbiology, University of Sydney, New South Wales, Australia.

出版信息

J Bacteriol. 1988 Jan;170(1):103-7. doi: 10.1128/jb.170.1.103-107.1988.

DOI:10.1128/jb.170.1.103-107.1988
PMID:2447059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC210612/
Abstract

The O antigens of Salmonella serogroups A, B, and D differ structurally in their side-chain sugar residue. These genes encoding O-antigen biosynthesis are clustered in the rfb operon. We report here the molecular cloning and analysis of the rfb operons of Salmonella paratyphi A (serogroup A) and S. typhi (serogroup D). The regions of DNA nonhomology between the rfb operons of these serogroup A, B, and D representatives are identified, and the evolutionary derivation of serogroup A from a serogroup D progenitor is discussed.

摘要

沙门氏菌A、B和D血清群的O抗原在其侧链糖残基的结构上有所不同。这些编码O抗原生物合成的基因聚集在rfb操纵子中。我们在此报告甲型副伤寒沙门氏菌（A血清群）和伤寒沙门氏菌（D血清群）rfb操纵子的分子克隆及分析。确定了这些A、B和D血清群代表菌的rfb操纵子之间的DNA非同源区域，并讨论了A血清群从D血清群祖先进化而来的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/5e400ee691db/jbacter00179-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/8db04660e973/jbacter00179-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/9736769630de/jbacter00179-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/6c8581cd0335/jbacter00179-0124-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/5e400ee691db/jbacter00179-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/8db04660e973/jbacter00179-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/9736769630de/jbacter00179-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/6c8581cd0335/jbacter00179-0124-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb02/210612/5e400ee691db/jbacter00179-0125-a.jpg

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