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编码鼠伤寒沙门氏菌LT2 O抗原生物合成酶的rfb基因簇的完整物理图谱。

Complete physical map of the rfb gene cluster encoding biosynthetic enzymes for the O antigen of Salmonella typhimurium LT2.

作者信息

Brahmbhatt H N, Wyk P, Quigley N B, Reeves P R

机构信息

Department of Microbiology, University of Sydney, New South Wales, Australia.

出版信息

J Bacteriol. 1988 Jan;170(1):98-102. doi: 10.1128/jb.170.1.98-102.1988.

DOI:10.1128/jb.170.1.98-102.1988
PMID:2447067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC210611/
Abstract

Biosynthesis of the Salmonella typhimurium LT2 O antigen is encoded by genes which map in the rfb cluster. The cloning and restriction enzyme analysis of part of this cluster have been described previously (H. N. Brahmbhatt, N. B. Quigley, and P. R. Reeves, Mol. Gen. Genet. 203:172-176, 1986). The entire rfb gene cluster has now been cloned, and a detailed restriction enzyme map has been constructed which has enabled us to map the approximate positions of individual rfb genes.

摘要

鼠伤寒沙门氏菌LT2 O抗原的生物合成由位于rfb基因簇中的基因编码。此前已描述了该基因簇部分区域的克隆和限制性内切酶分析(H. N. Brahmbhatt、N. B. Quigley和P. R. Reeves,《分子与普通遗传学》203:172 - 176,1986年)。现在整个rfb基因簇已被克隆,并构建了详细的限制性内切酶图谱,这使我们能够确定各个rfb基因的大致位置。

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