Labarbera Matthew, Jacobson Lester B
California Pacific Medical Center, San Francisco, California, CA, USA.
Infect Dis Rep. 2011 Oct 25;3(2):e12. doi: 10.4081/idr.2011.e12. eCollection 2011 Sep 7.
Invasive aspergillosis is an often fatal disease that usually occurs in immunocompromised patients. We report a case of invasive aspergillosis presenting as a febrile respiratory infection with a cardiac mass in an immunocompetent patient. Invasive asper-gillosis should be considered in the differential diagnosis of an otherwise undiagnosed invasive febrile respiratory illness, even in immunocompetent patients. Echocardiography should be performed to evaluate for endocarditis in such cases. Prompt initiation of appropriate antifungal therapy is warranted, even before the diagnosis of invasive aspergillosis is confirmed.
侵袭性曲霉病是一种通常发生在免疫功能低下患者中的常致命疾病。我们报告了一例侵袭性曲霉病,该病例在一名免疫功能正常的患者中表现为发热性呼吸道感染并伴有心脏肿物。即使在免疫功能正常的患者中,对于原因不明的侵袭性发热性呼吸道疾病进行鉴别诊断时也应考虑侵袭性曲霉病。在此类病例中应进行超声心动图检查以评估是否存在心内膜炎。即使在侵袭性曲霉病确诊之前,也有必要迅速开始适当的抗真菌治疗。