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青霉素过敏患者中由巴斯德菌引起的人工瓣膜心内膜炎:诊断和治疗中的挑战

Prosthetic valve endocarditis caused by Pasteurella in a penicillin allergic patient: challenges in diagnosis and treatment.

作者信息

Satta Giovanni, Gorton Rebecca Louise, Kandil Hala

机构信息

Department of Medical Microbiology, Royal Free London NHS Foundation Trust, London, UK.

出版信息

Infect Dis Rep. 2012 Apr 27;4(2):e32. doi: 10.4081/idr.2012.e32.

Abstract

Pasteurella multocida is a rare cause of infective endocarditis with only a few cases described. This report involves a 38-year-old penicillin-allergic patient in an immunocompromised state with several co-morbidities. Two molecular microbiological techniques, 16S rRNA sequencing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry were used to confirm the species identification as P. multocida. Previous reports in the literature are also reviewed.

摘要

多杀巴斯德菌是感染性心内膜炎的罕见病因,仅有少数病例报道。本报告涉及一名38岁的青霉素过敏患者,该患者处于免疫功能低下状态且患有多种合并症。采用两种分子微生物学技术,即16S rRNA测序和基质辅助激光解吸/电离飞行时间质谱法,以确认该菌种为多杀巴斯德菌。本文还对文献中的既往报道进行了综述。

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