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神经囊尾蚴病:一种被忽视的疾病。

Neurocysticercosis: A disease of neglect.

作者信息

Mewara Abhishek, Goyal Kapil, Sehgal Rakesh

机构信息

Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Trop Parasitol. 2013 Jul;3(2):106-13. doi: 10.4103/2229-5070.122111.

Abstract

Neurocysticercosis (NCC) is a neglected tropical disease caused by larval forms of the parasite Taenia solium lodging in central nervous system (CNS). There is a huge morbidity and debilitation due to CNS manifestations of NCC in developing and underdeveloped regions of the globe, mainly Asian, African and Latin American countries. It is the cause of epilepsy in about 1% of the population of endemic countries and is the underlying etiology in about 15-50% persons with epilepsy, depending upon the geographical region. There is no perfect diagnostic method and the diagnosis relies on a combination of clinical, radio-imaging, immunologic and epidemiologic data. Treatment includes anti-parasitic treatment by cysticidal drugs and management of associated symptoms and complications. The disease is eradicable and control depends on an integrated and coordinated involvement of international bodies like the World Health Organization along with scientific institutions and political and administrative strata of the endemic countries to provide the essential tools such as adequate sanitation, live-stock management, health education and improved socio-economic conditions.

摘要

神经囊尾蚴病(NCC)是一种被忽视的热带病,由寄生虫猪带绦虫的幼虫寄生于中枢神经系统(CNS)引起。在全球发展中及欠发达地区,主要是亚洲、非洲和拉丁美洲国家,由于NCC的中枢神经系统表现,导致了巨大的发病率和机体衰弱。在流行国家约1%的人口中,它是癫痫的病因,并且根据地理区域不同,在约15 - 50%的癫痫患者中是潜在病因。目前尚无完美的诊断方法,诊断依赖于临床、放射影像学、免疫学和流行病学数据的综合。治疗包括使用杀囊药物进行抗寄生虫治疗以及对相关症状和并发症的处理。该疾病是可根除的,其控制依赖于世界卫生组织等国际机构与科学机构以及流行国家的政治和行政层面的综合协调参与,以提供诸如适当的卫生设施、牲畜管理、健康教育和改善社会经济条件等基本手段。

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