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实时 PCR 法检测生活在法国的神经囊虫病患者脑脊液样本中的囊虫。

Confirmation and follow-up of neurocysticercosis by real-time PCR in cerebrospinal fluid samples of patients living in France.

机构信息

Laboratoire de Parasitologie Mycologie, Hôpital Cochin-Port Royal, AP-HP, Université Paris Descartes, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France.

出版信息

J Clin Microbiol. 2011 Dec;49(12):4338-40. doi: 10.1128/JCM.05839-11. Epub 2011 Oct 5.

DOI:10.1128/JCM.05839-11
PMID:21976768
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3232946/
Abstract

Neurocysticercosis diagnosis is based on a combination of clinical, epidemiological, radiological, and immunological findings. We describe a real-time PCR assay for the confirmation of neurocysticercosis diagnosis in cerebrospinal fluid. The assay, tested on samples from nine patients living in France and diagnosed with neurocysticercosis, had a detection rate of 83.3% and 100% specificity.

摘要

神经囊虫病的诊断基于临床、流行病学、影像学和免疫学检查的综合结果。我们描述了一种实时 PCR 检测方法,用于确认脑脊液中的神经囊虫病诊断。该检测方法在 9 名居住在法国并被诊断为神经囊虫病的患者样本中进行了测试,其检测率为 83.3%,特异性为 100%。

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本文引用的文献

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J Clin Microbiol. 2011 Jan;49(1):195-200. doi: 10.1128/JCM.01554-10. Epub 2010 Nov 10.
2
Taenia solium DNA is present in the cerebrospinal fluid of neurocysticercosis patients and can be used for diagnosis.猪带绦虫DNA存在于神经囊尾蚴病患者的脑脊液中,可用于诊断。
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