Dipartimento di Chimica, Università degli Studi di Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.
Dipartimento di Chimica, Università degli Studi di Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.
J Chromatogr A. 2014 Feb 28;1331:1-9. doi: 10.1016/j.chroma.2014.01.012. Epub 2014 Jan 15.
Wearable solid phase microextraction (SPME) devices consisting in necklaces and pins were developed for the environmental monitoring of ketamine in recreational places using ionic liquid as coating. SPME fibers obtained using both monocationic and dicationic polymeric ionic liquids were characterized in terms of morphology, film thickness, thermal stability and pH resistance. An average thickness of 30±5μm, an excellent thermal stability until 350°C and a very good fiber-to-fiber and batch-to-batch repeatability with RSD lower than 4% were some of the features of the developed coatings. A quantitation limit (LOQ) of 0.05mg/m(3) with a sampling time of 1min proved the feasibility of the developed method for the quantitation of ketamine in air at low concentration levels. Finally, the capabilities of the fibers for the rapid SPME sampling of ketamine in recreational places were proved obtaining extraction efficiencies at least two-fold higher than those obtained using commercial devices and extraction recoveries ranging from 84.2±3.3% to 93.6±2.6% (n=3).
开发了由项链和别针组成的可佩戴固相微萃取 (SPME) 装置，用于使用离子液体作为涂层，对娱乐场所中的氯胺酮进行环境监测。采用单阳离子和双阳离子聚合离子液体获得的 SPME 纤维在形态、膜厚度、热稳定性和耐 pH 值方面进行了表征。所开发涂层的一些特点包括：平均厚度为 30±5μm、极好的热稳定性直至 350°C 以及非常好的纤维间和批间重复性，RSD 低于 4%。采样时间为 1min 时，LOQ 为 0.05mg/m(3)，证明了该方法用于定量空气中低浓度氯胺酮的可行性。最后，通过证明在娱乐场所中快速 SPME 采样氯胺酮的纤维能力，获得了至少比使用商业设备高两倍的萃取效率，萃取回收率范围为 84.2±3.3%至 93.6±2.6%（n=3）。
