关于精油中苯丙素类化合物抗炎活性的综述。
A review on anti-inflammatory activity of phenylpropanoids found in essential oils.
作者信息
de Cássia da Silveira E Sá Rita, Andrade Luciana Nalone, Dos Reis Barreto de Oliveira Rafael, de Sousa Damião Pergentino
机构信息
Departamento de Fisiologia e Patologia, Universidade Federal da Paraíba, CP 5009, João Pessoa CEP 58051-970, PB, Brazil.
Departamento de Farmácia, Universidade Federal de Sergipe, São Cristóvão-SE, CEP 49100-000, SE, Brazil.
出版信息
Molecules. 2014 Jan 27;19(2):1459-80. doi: 10.3390/molecules19021459.
Abstract
The search for alternative drugs capable of disrupting the inflammatory process has become an important issue in scientific research, especially with reference to the use of natural substances and the reduction of undesirable side effects. Essential oils represent an important source of such substances, since their active constituents often exhibit an array of pharmacological properties, including anti-inflammatory activity. This review presents an overview of the anti-inflammatory action exerted by phenylpropanoids from essential oils and discusses possible mechanisms of action involved in the anti-inflammatory response, assessed through specific experimental models.
摘要
寻找能够干扰炎症过程的替代药物已成为科学研究中的一个重要问题，特别是在天然物质的使用以及减少不良副作用方面。精油是这类物质的重要来源，因为其活性成分通常具有一系列药理特性，包括抗炎活性。本综述概述了精油中苯丙素类化合物的抗炎作用，并讨论了通过特定实验模型评估的抗炎反应中可能涉及的作用机制。
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