精油的镇痛潜力。
Analgesic Potential of Essential Oils.
作者信息
Sarmento-Neto José Ferreira, do Nascimento Lázaro Gomes, Felipe Cícero Francisco Bezerra, de Sousa Damião Pergentino
机构信息
Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, CEP 58.051-900 João Pessoa-PB, Brazil.
Departamento de Biologia Molecular, Universidade Federal da Paraíba, CEP 58.051-900 João Pessoa-PB, Brazil.
出版信息
Molecules. 2015 Dec 23;21(1):E20. doi: 10.3390/molecules21010020.
Abstract
Pain is an unpleasant sensation associated with a wide range of injuries and diseases, and affects approximately 20% of adults in the world. The discovery of new and more effective drugs that can relieve pain is an important research goal in both the pharmaceutical industry and academia. This review describes studies involving antinociceptive activity of essential oils from 31 plant species. Botanical aspects of aromatic plants, mechanisms of action in pain models and chemical composition profiles of the essential oils are discussed. The data obtained in these studies demonstrate the analgesic potential of this group of natural products for therapeutic purposes.
摘要
疼痛是一种与多种损伤和疾病相关的不愉快感觉，全世界约20%的成年人受其影响。发现能够缓解疼痛的新型且更有效的药物是制药行业和学术界的一个重要研究目标。本综述描述了涉及31种植物精油抗伤害感受活性的研究。讨论了芳香植物的植物学特征、在疼痛模型中的作用机制以及精油的化学成分概况。这些研究中获得的数据证明了这类天然产物用于治疗目的的镇痛潜力。
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