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老年和成年大熊猫（Ailuropoda melanoleuca）肠道中的微生物多样性和新型同型乙酰生成菌证据。

Microbial diversity and evidence of novel homoacetogens in the gut of both geriatric and adult giant pandas (Ailuropoda melanoleuca).

机构信息

School of Biological Sciences, The University of Hong Kong, Hong Kong, Hong Kong SAR.

Department of Pathology, The University of Hong Kong, Hong Kong, Hong Kong SAR ; Hong Kong Wildlife Health Foundation, Hong Kong, Hong Kong SAR.

出版信息

PLoS One. 2014 Jan 24;9(1):e79902. doi: 10.1371/journal.pone.0079902. eCollection 2014.

DOI:10.1371/journal.pone.0079902
PMID:24475017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3901650/
Abstract

Recent studies have described the bacterial community residing in the guts of giant pandas, together with the presence of lignocellulolytic enzymes. However, a more comprehensive understanding of the intestinal microbial composition and its functional capacity in giant pandas remains a major goal. Here, we conducted a comparison of bacterial, fungal and homoacetogenic microbial communities from fecal samples taken from two geriatric and two adult captive giant pandas. 16S rDNA amplicon pyrosequencing revealed that Firmicutes and Proteobacteria are the most abundant microbiota in both geriatric and adult giant pandas. However, members of phylum Actinobacteria found in adult giant pandas were absent in their geriatric counterparts. Similarly, ITS1 amplicon pyrosequencing identified developmental changes in the most abundant fungal classes from Sordariomycetes in adult pandas to Saccharomycetes in geriatric pandas. Geriatric pandas exhibited significantly higher abundance of a potential probiotic fungus (Candida tropicalis) as compared to adult pandas, indicating their importance in the normal digestive physiology of aged pandas. Our study also reported the presence of a lignocellulolytic white-rot fungus, Perenniporia medulla-panis, and the evidence of novel homoacetogens residing in the guts of giant pandas.

摘要

最近的研究描述了大熊猫肠道中栖息的细菌群落，以及木质纤维素酶的存在。然而，更全面地了解大熊猫肠道微生物的组成及其功能能力仍然是一个主要目标。在这里，我们比较了来自两只老年和两只成年圈养大熊猫粪便样本中的细菌、真菌和同型产乙酸菌微生物群落。16S rDNA 扩增子焦磷酸测序显示，厚壁菌门和变形菌门是老年和成年大熊猫中最丰富的微生物群。然而，在老年大熊猫中没有发现成年大熊猫中存在的放线菌门成员。同样，ITS1 扩增子焦磷酸测序确定了从成年大熊猫中的 Sordariomycetes 到老年大熊猫中的 Saccharomycetes 最丰富的真菌类群的发育变化。与成年大熊猫相比，老年大熊猫中一种潜在的益生菌真菌（热带假丝酵母）的丰度显著增加，表明其在老年大熊猫正常消化生理中的重要性。我们的研究还报告了木质纤维素分解白腐真菌 Perenniporia medulla-panis 的存在，以及栖息在大熊猫肠道中的新型同型产乙酸菌的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/9401deff5280/pone.0079902.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/98238a59776a/pone.0079902.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/7a1697e8d521/pone.0079902.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/44740fabd006/pone.0079902.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/52c65932f8c0/pone.0079902.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/9401deff5280/pone.0079902.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/98238a59776a/pone.0079902.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/7a1697e8d521/pone.0079902.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/44740fabd006/pone.0079902.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/52c65932f8c0/pone.0079902.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db8/3901650/9401deff5280/pone.0079902.g005.jpg

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