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1例社区获得性耐甲氧西林金黄色葡萄球菌引起的急性化脓性骶髂关节炎和菌血症

A Case of Acute Pyogenic Sacroiliitis and Bacteremia Caused by Community-Acquired Methicillin-Resistant Staphylococcus aureus.

作者信息

Kim Suyoung, Lee Kang Lock, Baek Hae Lim, Jang Seung Jun, Moon Song Mi, Cho Yong Kyun

机构信息

Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.

Division of Infectious Disease, Gachon University Gil Medical Center, Incheon, Korea.

出版信息

Infect Chemother. 2013 Dec;45(4):441-5. doi: 10.3947/ic.2013.45.4.441. Epub 2013 Dec 27.

Abstract

Pyogenic sacroiliitis is a rare osteoarticular infection, occurring most frequently in children and young adults. Diagnosis of the disease is challenging because of a general lack of awareness of the disease and its nonspecific signs and symptoms. Staphylococcus aureus is the most common causative bacteria in pyogenic sacroiliitis. Methicillin-resistant S. aureus (MRSA) has typically been considered a hospital-associated pathogen; however, community-acquired (CA)-MRSA infections are becoming increasingly common in Korea. We report the first domestic case of acute pyogenic sacroiliitis with abscess and bacteremia caused by CA-MRSA. The pathogen carried the type IV-A staphylococcal cassette chromosome mec (SCCmec) without the Panton-Valentine leukocidin (PVL) gene, and was identified as sequence type (ST) 72 by multilocus sequence typing.

摘要

化脓性骶髂关节炎是一种罕见的骨关节炎感染,最常发生于儿童和年轻人。由于对该疾病普遍缺乏认识以及其非特异性体征和症状,该病的诊断具有挑战性。金黄色葡萄球菌是化脓性骶髂关节炎最常见的致病菌。耐甲氧西林金黄色葡萄球菌(MRSA)通常被认为是一种与医院相关的病原体;然而,社区获得性(CA)-MRSA感染在韩国正变得越来越普遍。我们报告了首例由CA-MRSA引起的伴有脓肿和菌血症的急性化脓性骶髂关节炎的国内病例。该病原体携带IV-A型葡萄球菌盒式染色体mec(SCCmec),但没有杀白细胞素(PVL)基因,并通过多位点序列分型被鉴定为序列型(ST)72。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54e0/3902811/7e36a225a3ab/ic-45-441-g001.jpg

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