抗磷脂综合征：一种具有多种表现的疾病。
Antiphospholipid syndrome: A disease of protean face.
作者信息
Ardalan Mohammadreza, Vahedi Amir
机构信息
Chronic Kidney Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Pathology, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
J Nephropathol. 2013 Jan;2(1):81-4. doi: 10.5812/nephropathol.9001. Epub 2013 Jan 1.
BACKGROUND
Antiphospholipid syndrome (APS) is a systemic disorder characterizes by recurrent arterial and venous thrombosis and/or pregnancy miscarriages and positive test for antiphospholipid antibodies.
CASE
Here we report a 31 year-old female whose main complain was symmetrical motor polyneuropathy and hand muscular weakness over a long period of time. Her clinical picture became more complex by Mitral valve regurgitation and renal dysfunction. Finally with the diagnosis of APS glucocorticoid therapy was started and her renal dysfunction improved profoundly, however her cardiac valvular involvement and peripheral neuropathy remained.
CONCLUSIONS
APS is a disease with wide clinical presentations and it continues to confound the clinicians.
背景
抗磷脂综合征（APS）是一种系统性疾病，其特征为反复发生动静脉血栓形成和/或妊娠流产以及抗磷脂抗体检测呈阳性。
病例
我们在此报告一名31岁女性，其主要主诉为长期对称性运动性多发性神经病和手部肌肉无力。二尖瓣反流和肾功能不全使她的临床情况变得更加复杂。最终，在诊断为APS后开始了糖皮质激素治疗，她的肾功能得到了显著改善，然而她的心脏瓣膜受累和周围神经病变仍然存在。
结论
APS是一种临床表现广泛的疾病，仍然使临床医生感到困惑。
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