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Epidemiology of the 2009 influenza pandemic in Spain. The Spanish Influenza Surveillance System.西班牙 2009 年流感大流行的流行病学。西班牙流感监测系统。
Enferm Infecc Microbiol Clin. 2012 Oct;30 Suppl 4:2-9. doi: 10.1016/S0213-005X(12)70098-8.
2
Influenza-related mortality in Spain, 1999-2005.1999 - 2005年西班牙流感相关死亡率
Gac Sanit. 2012 Jul-Aug;26(4):325-9. doi: 10.1016/j.gaceta.2011.09.033. Epub 2012 Jan 28.
3
Geographic trends and spread of the pandemic (H1N1) 2009 in the metropolitan areas of Japan studied from the national sentinel data.从全国监测数据研究日本都市区 2009 年大流行（H1N1）的地理趋势和传播。
Jpn J Infect Dis. 2011;64(6):473-81.
4
Spatial and temporal characteristics of the 2009 A/H1N1 influenza pandemic in Peru.秘鲁 2009 年甲型 H1N1 流感大流行的时空特征。
PLoS One. 2011;6(6):e21287. doi: 10.1371/journal.pone.0021287. Epub 2011 Jun 21.
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Characterizing the epidemiology of the 2009 influenza A/H1N1 pandemic in Mexico.描述墨西哥 2009 年甲型 H1N1 流感大流行的流行病学特征。
PLoS Med. 2011 May;8(5):e1000436. doi: 10.1371/journal.pmed.1000436. Epub 2011 May 24.
6
[Surveillance of influenza pandemic (H1N1)2009 in Spain].[2009年西班牙甲型H1N1流感大流行监测]
Rev Esp Salud Publica. 2010 Sep-Oct;84(5):569-88. doi: 10.1590/s1135-57272010000500009.
7
A kernel-based spatio-temporal surveillance system for monitoring influenza-like illness incidence.基于核的时空监测系统，用于监测流感样疾病发病率。
Stat Methods Med Res. 2011 Apr;20(2):103-18. doi: 10.1177/0962280210370265. Epub 2010 Jun 2.
8
Emergence of a novel swine-origin influenza A (H1N1) virus in humans.一种新型猪源甲型流感病毒（H1N1）在人类中的出现。
N Engl J Med. 2009 Jun 18;360(25):2605-15. doi: 10.1056/NEJMoa0903810. Epub 2009 May 7.
9
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J Epidemiol. 2007 Dec;17 Suppl(Suppl):S32-41. doi: 10.2188/jea.17.s32.
10
Influenza activity in Europe during eight seasons (1999-2007): an evaluation of the indicators used to measure activity and an assessment of the timing, length and course of peak activity (spread) across Europe.欧洲八个流感季节（1999 - 2007年）的流感活动情况：对用于衡量流感活动的指标进行评估，并对欧洲各地流感活动高峰（传播）的时间、持续时长和过程进行评估。
BMC Infect Dis. 2007 Nov 30;7:141. doi: 10.1186/1471-2334-7-141.

西班牙 2009 年甲型 H1N1 流感大流行期间及随后两个流感季节流感发病率的地域分布。

Geographical spread of influenza incidence in Spain during the 2009 A(H1N1) pandemic wave and the two succeeding influenza seasons.

机构信息

CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid,Spain.

Centro Superior de Investigación en Salud Pública (CSISP-FISABIO), Valencia,Spain.

出版信息

Epidemiol Infect. 2014 Dec;142(12):2629-41. doi: 10.1017/S0950268813003439. Epub 2014 Jan 27.

DOI:10.1017/S0950268813003439
PMID:24476599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9151274/
Abstract

The aim of this study was to monitor the spatio-temporal spread of influenza incidence in Spain during the 2009 pandemic and the following two influenza seasons 2010-2011 and 2011-2012 using a Bayesian Poisson mixed regression model; and implement this model of geographical analysis in the Spanish Influenza Surveillance System to obtain maps of influenza incidence for every week. In the pandemic wave the maps showed influenza activity spreading from west to east. The 2010-2011 influenza epidemic wave plotted a north-west/south-east pattern of spread. During the 2011-2012 season the spread of influenza was geographically heterogeneous. The most important source of variability in the model is the temporal term. The model of spatio-temporal spread of influenza incidence is a supplementary tool of influenza surveillance in Spain.

摘要

本研究旨在使用贝叶斯泊松混合回归模型监测 2009 年大流行期间以及随后的 2010-2011 年和 2011-2012 年流感季节期间西班牙流感发病率的时空传播情况；并在西班牙流感监测系统中实施这种地理分析模型，以获得每周的流感发病率图。在大流行期间，地图显示流感活动从西向东传播。2010-2011 年流感流行波呈现出西北/东南传播模式。在 2011-2012 季节期间，流感的传播具有地域异质性。模型中最重要的可变性来源是时间项。流感发病率时空传播模型是西班牙流感监测的补充工具。