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[2009年西班牙甲型H1N1流感大流行监测]

[Surveillance of influenza pandemic (H1N1)2009 in Spain].

作者信息

Larrauri Cámara Amparo, Jiménez-Jorge Silvia, Simón Méndez Lorena, de Mateo Ontañón Salvador

机构信息

Área de Vigilancia de la Salud Pública, Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain.

出版信息

Rev Esp Salud Publica. 2010 Sep-Oct;84(5):569-88. doi: 10.1590/s1135-57272010000500009.

Abstract

BACKGROUND

During the summer of 2009, Spain experienced the circulation of the novel influenza (H1N1)2009 virus, beyond the usual period of influenza activity, increasingly evolving up to the presentation in the early autumn of the first wave of the pandemic virus. The objectives of this study are to describe the evolution of the pandemic wave in our country and to assess their impact on morbidity and mortality of the Spanish population.

METHOD

From the information obtained from the Spanish Influenza Surveillance System and the Coordinating Centre for Health Alerts and Emergencies within Spanish Ministry of Health and Social Policy have been estimated a number of epidemiological and virological indicators that were used to assess the level of activity and intensity of the pandemic wave, as well as its severity

RESULTS

The beginning of the pandemic wave in Spain started in early autumn 2009 reaching the maximum weekly incidence rate of 372.15 cases/100,000 inhabitants. The highest incidence was registered in under 15 years old. Viral detection rate registered during the pandemic period remained at the range of previously recorded (46.4%). We estimated an overall mortality rate of 0.43 deaths per 1,000 pandemic cases. The 64% of deaths from pandemic influenza occurred in young adults and the highest mortality rates were registered in the 45-64 years age group with 9.35 deaths/1,000,000 inhabitants. Mortality associated with seasonal influenza in the period 2001-2008 was highest in those over 64 years (95% of all deaths).

CONCLUSIONS

The influenza (H1N1)2009 pandemic wave in Spain showed an early presentation and a medium level of influenza intensity compared to the previous thirteen seasonal influenza waves. Considering lethality or mortality rates, this first pandemic wave was also characterized by a mild severity, although a high percentage of deaths confirmed by the new virus were observed in population under 65 years.

摘要

背景

2009年夏季,西班牙出现新型甲型H1N1流感病毒传播,超出了流感活动的正常时期,疫情不断发展,直至初秋出现了第一波大流行病毒。本研究的目的是描述我国大流行波的演变情况,并评估其对西班牙人群发病率和死亡率的影响。

方法

从西班牙流感监测系统以及西班牙卫生和社会政策部下属的卫生警报与应急协调中心获取信息,估算了一些流行病学和病毒学指标,用于评估大流行波的活动水平、强度及其严重程度。

结果

西班牙大流行波始于2009年秋初,每周发病率最高达到372.15例/10万居民。发病率最高的是15岁以下人群。大流行期间的病毒检测率维持在先前记录的范围内(46.4%)。我们估计每1000例大流行病例的总死亡率为0.43例。64%的甲型H1N1流感死亡病例发生在年轻人中,死亡率最高的是45 - 64岁年龄组,为9.35例/100万居民。2001 - 2008年期间,季节性流感相关死亡率在64岁以上人群中最高(占所有死亡病例的95%)。

结论

与之前的13次季节性流感波相比,西班牙的甲型H1N1流感2009大流行波出现较早,流感强度为中等水平。考虑到致死率或死亡率,这第一波大流行波的特点也是严重程度较轻,尽管在65岁以下人群中观察到新病毒确诊的死亡病例比例较高。

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