Singer F, Kolarz G, Thumb N, Schieler K
Rehabilitationszentrum für Rheumakranke und Bewegungsbehinderte der PVArb/Bad Schallerbach.
Z Rheumatol. 1987 Sep-Oct;46(5):245-9.
Synovial fluids of patients suffering from rheumatoid arthritis and osteoarthritis with effusions of the knees were examined. Different parameters were evaluated out of the synovial fluid (immunglobulins, Complement-1Q,-3,-4, haptoglobins, alpha-1-anti-trypsin, alpha-2-macroglobulin, transferrin, ceruloplasmin, rheumatoid factors, total count of cells, and ragocytes) and out of the plasma (blood sedimentation rate). The proteins were analysed by a nephelometricturbidimetric automatic centrifugal analyser. All parameters have been tested by valuable statistical methods and correlated to each other. The results worked out proved the reliability of the used test kits and apparative systems. Correlations within groups of parameters according to their formations (intra-and/or extraarticular) could not have been worked out in a way as it may be supposed. In contrast some parameters themselves are statistically different comparing rheumatoid arthritis and osteoarthritis. In general the results are on a higher level in the rheumatoid arthritis group. Using all parameters mentioned above the statistical differential diagnostic level is based on about 94%. If only blood sedimentation rate, total cell count and ragocytes are evaluated the level is based on 68%.
对患有类风湿性关节炎和骨关节炎且膝关节有积液的患者的滑液进行了检查。从滑液（免疫球蛋白、补体 -1Q、-3、-4、触珠蛋白、α-1-抗胰蛋白酶、α-2-巨球蛋白、转铁蛋白、铜蓝蛋白、类风湿因子、细胞总数和吞噬细胞）和血浆（血沉率）中评估了不同参数。蛋白质通过散射比浊自动离心分析仪进行分析。所有参数均通过有价值的统计方法进行测试并相互关联。得出的结果证明了所使用的检测试剂盒和仪器系统的可靠性。根据参数的形成方式（关节内和/或关节外）在参数组内的相关性无法按预期方式得出。相比之下，类风湿性关节炎和骨关节炎的一些参数本身在统计学上存在差异。总体而言，类风湿性关节炎组的结果处于较高水平。使用上述所有参数，统计鉴别诊断水平约为94%。如果仅评估血沉率、细胞总数和吞噬细胞，该水平为68%。
