Bálint Z S
National Institute of Oncology, Budapest, Hungary.
Basic Appl Histochem. 1987;31(3):365-76.
Lipid content and composition of DNA, histone and non-histone proteins of Ehrlich ascites tumor cell chromatin were investigated. All fractions contained small amounts of lipids, mostly neutral ones, in a specific distribution. According to isotopic studies with labeled lipid precursors, incorporation took place mainly in the non-histone fraction. These findings suggest that neutral lipids attached to non-histone chromosomal proteins may also contribute to the regulatory functions ascribed to phospholipids.
对艾氏腹水瘤细胞染色质的DNA、组蛋白和非组蛋白的脂质含量及组成进行了研究。所有组分都含有少量脂质，主要是中性脂质，呈特定分布。根据用标记脂质前体进行的同位素研究，掺入主要发生在非组蛋白组分中。这些发现表明，附着于非组蛋白染色体蛋白的中性脂质也可能有助于发挥归因于磷脂的调节功能。
