艾氏腹水瘤细胞染色质的DNA、组蛋白和非组蛋白组分中的中性脂质
Neutral lipids in DNA, histone and nonhistone fractions of Ehrlich ascites tumor cell chromatin.
作者信息
Bálint Z, Holczinger L
出版信息
Cancer Biochem Biophys. 1979;3(4):193-6.
Lipid content and composition of DNA, histone and nonhistone proteins of Ehrlich ascites tumor cell chromatin were investigated. All fractions contained varying amounts of lipids, mostly neutral lipids, with different quantitative distribution. The DNA fraction was characterized by elevated total cholesterol level (37%); the histone fraction by high glycerol ester content (62%); and the nonhistone protein fraction by high percentage of glycerol ethers (22%). The results suggest that neutral lipids are integral parts of tumor cell nucleoproteins.
对艾氏腹水瘤细胞染色质的DNA、组蛋白和非组蛋白的脂质含量及组成进行了研究。所有组分都含有不同量的脂质，主要是中性脂质，且具有不同的定量分布。DNA组分的特征是总胆固醇水平升高（37%）；组蛋白组分的特征是甘油酯含量高（62%）；非组蛋白组分的特征是甘油醚的百分比高（22%）。结果表明，中性脂质是肿瘤细胞核蛋白的组成部分。
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