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卵巢扭转:一项病例对照研究,比较超声检查和计算机断层扫描在急诊科诊断中的敏感性和特异性。

Ovarian torsion: Case-control study comparing the sensitivity and specificity of ultrasonography and computed tomography for diagnosis in the emergency department.

作者信息

Swenson David W, Lourenco Ana P, Beaudoin Francesca L, Grand David J, Killelea Alison G, McGregor Alyson J

机构信息

Alpert Medical School of Brown University, Department of Diagnostic Imaging, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, United States.

Alpert Medical School of Brown University, Department of Diagnostic Imaging, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, United States.

出版信息

Eur J Radiol. 2014 Apr;83(4):733-8. doi: 10.1016/j.ejrad.2014.01.001. Epub 2014 Jan 8.

Abstract

OBJECTIVE

Evaluate the sensitivity and specificity of pelvic ultrasound (US) and abdominopelvic computed tomography (CT) for the identification of ovarian torsion in women presenting to the emergency department with acute lower abdominal or pelvic pain.

MATERIALS AND METHODS

This is a retrospective study of 20 cases of ovarian torsion and 20 control patients, all of whom had both US and CT performed in the emergency department. Two radiologists who were blinded to clinical data interpreted all studies as (1) demonstrating an abnormal ovary or not, and (2) suggestive of torsion or not. Sensitivity, specificity and interobserver variation were calculated for each imaging modality.

RESULTS

Pelvic US was interpreted as demonstrating an abnormal ovary in 90.0% of ovarian torsion cases by reader 1, and in 100.0% by reader 2, whereas CT was interpreted as revealing an abnormal ovary in 100.0% of torsion cases by both readers. Pelvic US for ovarian torsion was 80.0% sensitive (95% CI, 58.4-91.9%) and 95.0% specific (95% CI, 76.4-99.1%) for reader 1, while 80.0% sensitive (95% CI, 58.4-91.9%) and 85.0% specific (95% CI, 64.0-95.0%) for reader 2. Interobserver agreement for pelvic US was fair (Kappa=0.60). Abdominopelvic CT for ovarian torsion was 100.0% sensitive (95% CI, 83.9-100.0%) and 85.0% specific (95% CI, 64.0-94.5%) for reader 1, while 90.0% sensitive (95% CI, 69.9-97.2%) and 90.0% specific (95% CI, 69.9-97.2%) for reader 2. Interobserver agreement was excellent (Kappa=0.85).

CONCLUSION

The diagnostic performance of CT is not shown to be significantly different from that of US in identifying ovarian torsion in this study. These results suggest that when CT demonstrates findings of ovarian torsion, the performance of another imaging exam (i.e. US) that delays therapy is unlikely to improve preoperative diagnostic yield.

摘要

目的

评估盆腔超声(US)和腹盆腔计算机断层扫描(CT)对急诊科出现急性下腹部或盆腔疼痛的女性卵巢扭转的诊断敏感性和特异性。

材料与方法

这是一项对20例卵巢扭转患者和20例对照患者的回顾性研究,所有患者均在急诊科接受了超声和CT检查。两位对临床数据不知情的放射科医生对所有检查结果进行解读,判断(1)是否显示卵巢异常,(2)是否提示扭转。计算每种成像方式的敏感性、特异性和观察者间差异。

结果

读者1将盆腔超声解读为在90.0%的卵巢扭转病例中显示卵巢异常,读者2的解读为100.0%;而两位读者将CT解读为在100.0%的扭转病例中显示卵巢异常。读者1对卵巢扭转的盆腔超声敏感性为80.0%(95%可信区间,58.4 - 91.9%),特异性为95.0%(95%可信区间,76.4 - 99.1%);读者2的敏感性为80.0%(95%可信区间,58.4 - 91.9%),特异性为85.0%(95%可信区间,64.0 - 95.0%)。盆腔超声的观察者间一致性一般(Kappa = 0.60)。读者1对卵巢扭转的腹盆腔CT敏感性为100.0%(95%可信区间,83.9 - 100.0%),特异性为85.0%(95%可信区间,64.0 - 94.5%);读者2的敏感性为90.0%(95%可信区间,69.9 - 97.2%),特异性为90.0%(95%可信区间,69.9 - 97.2%)。观察者间一致性良好(Kappa = 0.85)。

结论

在本研究中,CT在诊断卵巢扭转方面的表现与超声无显著差异。这些结果表明,当CT显示卵巢扭转的表现时,进行另一种会延迟治疗的成像检查(即超声)不太可能提高术前诊断率。

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