Bryson Thomas, Sundaram Baskaran, Khanna Dinesh, Kazerooni Ella A
Department of Diagnostic Radiology, University of Michigan Health System, Ann Arbor, MI.
Department of Diagnostic Radiology, University of Michigan Health System, Ann Arbor, MI.
Semin Ultrasound CT MR. 2014 Feb;35(1):29-38. doi: 10.1053/j.sult.2013.10.010. Epub 2013 Oct 24.
Interstitial lung diseases (ILDs) are increasingly recognized in patients with systemic diseases. Patients with early ILD changes may be asymptomatic. Features of ILD overlap among systemic diseases and with idiopathic variety. High-resolution computed tomography plays a central role in diagnosing ILDs. Imaging features are often nonspecific. Therapy- and complication-related lung changes would pose difficulty in diagnosing and classifying an ILD. Biology and prognosis of secondary ILDs may differ between different disease-related ILDs and idiopathic variety. Combination of clinical features, serological tests, pulmonary and extrapulmonary imaging findings, and pathology findings may help to diagnose ILDs.
间质性肺疾病（ILDs）在患有全身性疾病的患者中越来越多地被认识到。早期ILD改变的患者可能没有症状。ILD的特征在全身性疾病之间以及与特发性类型之间存在重叠。高分辨率计算机断层扫描在ILD的诊断中起着核心作用。影像学特征通常是非特异性的。与治疗和并发症相关的肺部改变会给ILD的诊断和分类带来困难。不同疾病相关的继发性ILDs与特发性类型在生物学和预后方面可能有所不同。临床特征、血清学检查、肺部和肺外影像学表现以及病理学发现的综合应用可能有助于ILD的诊断。
