社论：药物化学中的氟化作用与含氟化合物 - Suppr

Editorial: Fluorination and fluorinated compounds in medicinal chemistry.

作者信息

Altman Ryan A

机构信息

Department of Medicinal Chemistry The University of Kansas 1251 Wescoe Hall Drive 4046A Malott Hall Lawrence, KS 66045 USA.

出版信息

Curr Top Med Chem. 2014;14(7):837-9. doi: 10.2174/1568026614666140202203407.

DOI:10.2174/1568026614666140202203407

PMID:24484420

Abstract

摘要

相似文献

Editorial: Fluorination and fluorinated compounds in medicinal chemistry.

Curr Top Med Chem. 2014;14(7):837-9. doi: 10.2174/1568026614666140202203407.

Recent progress in asymmetric fluorination and trifluoromethylation reactions.

Curr Top Med Chem. 2014;14(7):901-40. doi: 10.2174/1568026614666140202205531.

Fluorination methods in drug discovery.

Org Biomol Chem. 2016 Sep 28;14(36):8398-427. doi: 10.1039/c6ob00764c. Epub 2016 Aug 10.

Asymmetric Preparation of -Quaternary Fluorinated -keto Esters. Review.

Molecules. 2020 Jul 17;25(14):3264. doi: 10.3390/molecules25143264.

Palladium-Catalyzed Site-Selective Fluorination of Unactivated C(sp(3))-H Bonds.

Org Lett. 2015 Aug 7;17(15):3738-41. doi: 10.1021/acs.orglett.5b01710. Epub 2015 Jul 24.

Synthesis of Fluorinated 3,6-Dihydropyridines and 2-(Fluoromethyl)pyridines by Electrophilic Fluorination of 1,2-Dihydropyridines with Selectfluor.

Molecules. 2020 Jul 9;25(14):3143. doi: 10.3390/molecules25143143.

Fluorine in medicinal chemistry.

Chem Soc Rev. 2008 Feb;37(2):320-30. doi: 10.1039/b610213c. Epub 2007 Dec 13.

Selective fluorination in drug design and development: an overview of biochemical rationales.

Curr Top Med Chem. 2006;6(14):1447-56. doi: 10.2174/156802606777951073.

Decarboxylative fluorination strategies for accessing medicinally- relevant products.

Curr Top Med Chem. 2014;14(7):966-78. doi: 10.2174/1568026614666140202210850.

Fluoroalkyl Amino Reagents (FARs): A General Approach towards the Synthesis of Heterocyclic Compounds Bearing Emergent Fluorinated Substituents.

Molecules. 2017 Jun 12;22(6):977. doi: 10.3390/molecules22060977.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Editorial: Fluorination and fluorinated compounds in medicinal chemistry.

作者信息

Altman Ryan A

机构信息

Department of Medicinal Chemistry The University of Kansas 1251 Wescoe Hall Drive 4046A Malott Hall Lawrence, KS 66045 USA.

出版信息

Curr Top Med Chem. 2014;14(7):837-9. doi: 10.2174/1568026614666140202203407.

DOI:10.2174/1568026614666140202203407

PMID:24484420

Abstract

摘要

相似文献

Editorial: Fluorination and fluorinated compounds in medicinal chemistry.

Curr Top Med Chem. 2014;14(7):837-9. doi: 10.2174/1568026614666140202203407.

Recent progress in asymmetric fluorination and trifluoromethylation reactions.

Curr Top Med Chem. 2014;14(7):901-40. doi: 10.2174/1568026614666140202205531.

Fluorination methods in drug discovery.

Org Biomol Chem. 2016 Sep 28;14(36):8398-427. doi: 10.1039/c6ob00764c. Epub 2016 Aug 10.

Asymmetric Preparation of -Quaternary Fluorinated -keto Esters. Review.

Molecules. 2020 Jul 17;25(14):3264. doi: 10.3390/molecules25143264.

Palladium-Catalyzed Site-Selective Fluorination of Unactivated C(sp(3))-H Bonds.

Org Lett. 2015 Aug 7;17(15):3738-41. doi: 10.1021/acs.orglett.5b01710. Epub 2015 Jul 24.

Synthesis of Fluorinated 3,6-Dihydropyridines and 2-(Fluoromethyl)pyridines by Electrophilic Fluorination of 1,2-Dihydropyridines with Selectfluor.

Molecules. 2020 Jul 9;25(14):3143. doi: 10.3390/molecules25143143.

Fluorine in medicinal chemistry.

Chem Soc Rev. 2008 Feb;37(2):320-30. doi: 10.1039/b610213c. Epub 2007 Dec 13.

Selective fluorination in drug design and development: an overview of biochemical rationales.

Curr Top Med Chem. 2006;6(14):1447-56. doi: 10.2174/156802606777951073.

Decarboxylative fluorination strategies for accessing medicinally- relevant products.

Curr Top Med Chem. 2014;14(7):966-78. doi: 10.2174/1568026614666140202210850.

Fluoroalkyl Amino Reagents (FARs): A General Approach towards the Synthesis of Heterocyclic Compounds Bearing Emergent Fluorinated Substituents.

Molecules. 2017 Jun 12;22(6):977. doi: 10.3390/molecules22060977.

Editorial: Fluorination and fluorinated compounds in medicinal chemistry.

作者信息

机构信息

出版信息

相似文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

Editorial: Fluorination and fluorinated compounds in medicinal chemistry.

作者信息

机构信息

出版信息

相似文献