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大鼠脑视前区中促黄体生成素释放激素染色神经元之间联系的显示。

Demonstration of contacts between neurons staining for LHRH in the preoptic area of the rat brain.

作者信息

Pelletier G

机构信息

MRC Group in Molecular Endocrinology, Le Centre Hospitalier de l'Université Laval, Ste-Foy, Qué., Canada.

出版信息

Neuroendocrinology. 1987 Nov;46(5):457-9. doi: 10.1159/000124861.

DOI:10.1159/000124861
PMID:2448700
Abstract

It has been recently demonstrated that luteinizing hormone-releasing hormone (LHRH) can inhibit LHRH release by the hypothalamus, suggesting an ultrashort feedback of LHRH on LHRH neurons. In order to test this hypothesis, immunocytochemical localization of LHRH was conducted in the preoptic area of the rat brain. Contacts between endings and neuronal cell bodies staining for LHRH were observed. This direct interaction between LHRH neurons might be well the morphological basis for an autoregulation of the LHRH system in the rat brain.

摘要

最近已证实，促黄体生成激素释放激素（LHRH）可抑制下丘脑释放LHRH，提示LHRH对LHRH神经元存在超短反馈。为验证这一假说，对大鼠脑视前区进行了LHRH的免疫细胞化学定位。观察到LHRH染色的终末与神经元细胞体之间的接触。LHRH神经元之间的这种直接相互作用很可能是大鼠脑内LHRH系统自动调节的形态学基础。

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Neuroendocrinology. 1987 Nov;46(5):457-9. doi: 10.1159/000124861.
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