利用超长扫描深度光学相干断层扫描测量调节时的全眼球轴向生物测量。
Whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography.
机构信息
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; Hangzhou First People's Hospital, Zhejiang, China.
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China.
出版信息
Am J Ophthalmol. 2014 May;157(5):1064-69. doi: 10.1016/j.ajo.2014.01.016. Epub 2014 Jan 30.
PURPOSE
To investigate changes of whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography (UL-OCT).
DESIGN
Prospective, observational case series.
METHODS
Twenty-one adult subjects were enrolled. Using UL-OCT, the left eye of each subject was imaged with relaxed diopters (0 D) and accommodative stimuli (+6 D). Full eye biometry included central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness, vitreous length, and axial length (AL).
RESULTS
During accommodation (+6 D), the axial biometry of the whole eye changed significantly. Compared to the rest state, ACD at the accommodative state decreased significantly from 3.128 ± 0.305 mm to 2.961 ± 0.298 mm (paired t test, P < .001). The lens thickness increased significantly from 3.723 ± 0.237 mm to 3.963 ± 0.234 mm (P < .001). The vitreous length decreased significantly from 17.129 ± 0.864 mm to 17.057 ± 0.848 mm (P < .001). AL was 24.519 ± 0.917 mm at the rest state and increased to 24.545 ± 0.915 mm with +6 D accommodation stimulus. The elongated AL of 26.1 ± 13.4 μm between the rest and accommodative states was significant (P < .001).
CONCLUSIONS
During accommodation, whole eye axial biometry changed, including a decrease in ACD and vitreous length and an increase in lens thickness and AL. UL-OCT provides an alternative method that is suitable for full eye biometry during accommodation.
目的
使用超长扫描深度光学相干断层扫描（UL-OCT）研究调节过程中整个眼球轴向生物测量的变化。
设计
前瞻性、观察性病例系列。
方法
共纳入 21 名成年受试者。使用 UL-OCT 对每个受试者的左眼进行放松屈光度（0 D）和调节刺激（+6 D）成像。全眼球生物测量包括中央角膜厚度（CCT）、前房深度（ACD）、晶状体厚度、玻璃体长度和眼轴（AL）。
结果
在调节（+6 D）状态下，整个眼球的轴向生物测量发生了显著变化。与休息状态相比，调节状态下的 ACD 显著从 3.128 ± 0.305 mm 下降至 2.961 ± 0.298 mm（配对 t 检验，P <.001）。晶状体厚度从 3.723 ± 0.237 mm 显著增加至 3.963 ± 0.234 mm（P <.001）。玻璃体长度从 17.129 ± 0.864 mm 显著下降至 17.057 ± 0.848 mm（P <.001）。在休息状态下，AL 为 24.519 ± 0.917 mm，在+6 D 调节刺激下增加至 24.545 ± 0.915 mm。在休息和调节状态之间，眼轴延长了 26.1 ± 13.4 μm，这一差异具有统计学意义（P <.001）。
结论
在调节过程中，整个眼球的轴向生物测量发生了变化，包括 ACD 和玻璃体长度的减少，晶状体厚度和 AL 的增加。UL-OCT 提供了一种适合调节过程中全眼球生物测量的替代方法。
Zotero 插件