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高危婴儿的饮食暴露与过敏预防:加拿大过敏与临床免疫学会和加拿大儿科学会的联合立场声明

Dietary exposures and allergy prevention in high-risk infants: a joint position statement of the Canadian Society of Allergy and Clinical Immunology and the Canadian Paediatric Society.

作者信息

Chan Edmond S, Cummings Carl, Atkinson Adelle, Chad Zave, Francoeur Marie-Josée, Kirste Linda, Mack Douglas, Primeau Marie-Noël, Vander Leek Timothy K, Watson Wade Ta

机构信息

BC Children's Hospital, Department of Pediatrics, Division of Allergy & Immunology, University of British Columbia, Room 1C31B, 4480 Oak St, Vancouver, BC V6H 3V4 Canada.

Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec Canada.

出版信息

Allergy Asthma Clin Immunol. 2014 Sep 2;10(1):45. doi: 10.1186/1710-1492-10-45. eCollection 2014.

DOI:10.1186/1710-1492-10-45
PMID:25908933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4407306/
Abstract

Allergic conditions in children are a prevalent health concern in Canada. The burden of disease and the societal costs of proper diagnosis and management are considerable, making the primary prevention of allergic conditions a desirable health care objective. This position statement reviews current evidence on dietary exposures and allergy prevention in infants at high risk of developing allergic conditions. It revisits previous dietary recommendations for pregnancy, breastfeeding and formula-feeding, and provides an approach for introducing solid foods to high-risk infants. While there is no evidence that delaying the introduction of any specific food beyond six months of age helps to prevent allergy, the protective effect of early introduction of potentially allergenic foods (at four to six months) remains under investigation. Recent research appears to suggest that regularly ingesting a new, potentially allergenic food may be as important as when that food is first introduced. This article has already been published (Paediatr Child Health. 2013 Dec;18(10):545-54), and is being re-published with permission from the original publisher, the Canadian Paediatric Society.

摘要

儿童过敏疾病是加拿大普遍关注的健康问题。疾病负担以及正确诊断和管理的社会成本相当可观,这使得预防过敏疾病成为理想的医疗保健目标。本立场声明回顾了有关高过敏风险婴儿饮食暴露与过敏预防的现有证据。它重新审视了先前关于孕期、母乳喂养和配方奶喂养的饮食建议,并提供了向高风险婴儿引入固体食物的方法。虽然没有证据表明在六个月龄后推迟引入任何特定食物有助于预防过敏,但早期引入潜在致敏食物(四至六个月龄)的保护作用仍在研究中。最近的研究似乎表明,定期摄入一种新的潜在致敏食物可能与首次引入该食物的时间同样重要。本文已发表(《儿科与儿童健康》。2013年12月;18(10):545 - 54),经原出版商加拿大儿科学会许可重新发表。

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本文引用的文献

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J Allergy Clin Immunol Pract. 2013 Jan;1(1):29-36. doi: 10.1016/j.jaip.2012.09.003. Epub 2012 Nov 22.
2
Introduction of complementary foods in infancy and atopic sensitization at the age of 5 years: timing and food diversity in a Finnish birth cohort.婴儿期辅食引入与 5 岁时特应性致敏:芬兰出生队列研究中的时间和食物多样性。
Allergy. 2013 Apr;68(4):507-16. doi: 10.1111/all.12118. Epub 2013 Feb 15.
3
Allergies in high-risk schoolchildren after early intervention with cow's milk protein hydrolysates: 10-year results from the German Infant Nutritional Intervention (GINI) study.高风险学龄儿童在早期干预食用牛奶蛋白水解物后的过敏反应:德国婴儿营养干预(GINI)研究的 10 年结果。
J Allergy Clin Immunol. 2013 Jun;131(6):1565-73. doi: 10.1016/j.jaci.2013.01.006. Epub 2013 Mar 16.
4
Nutrition for healthy term infants: recommendations from birth to six months.足月健康婴儿的营养:从出生到六个月的建议
Can J Diet Pract Res. 2012 Winter;73(4):204. doi: 10.3148/73.4.2012.204.
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Timing of infant feeding in relation to childhood asthma and allergic diseases.婴儿喂养时间与儿童哮喘和过敏性疾病的关系。
J Allergy Clin Immunol. 2013 Jan;131(1):78-86. doi: 10.1016/j.jaci.2012.10.028. Epub 2012 Nov 22.
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Identifying infants at high risk of peanut allergy: the Learning Early About Peanut Allergy (LEAP) screening study.识别花生过敏高危婴儿:学习早期关于花生过敏(LEAP)筛查研究。
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