Goldstein Andrea N, Walker Matthew P
Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720-1650; email:
Annu Rev Clin Psychol. 2014;10:679-708. doi: 10.1146/annurev-clinpsy-032813-153716. Epub 2014 Jan 31.
Rapidly emerging evidence continues to describe an intimate and causal relationship between sleep and emotional brain function. These findings are mirrored by long-standing clinical observations demonstrating that nearly all mood and anxiety disorders co-occur with one or more sleep abnormalities. This review aims to (a) provide a synthesis of recent findings describing the emotional brain and behavioral benefits triggered by sleep, and conversely, the detrimental impairments following a lack of sleep; (b) outline a proposed framework in which sleep, and specifically rapid-eye movement (REM) sleep, supports a process of affective brain homeostasis, optimally preparing the organism for next-day social and emotional functioning; and (c) describe how this hypothesized framework can explain the prevalent relationships between sleep and psychiatric disorders, with a particular focus on posttraumatic stress disorder and major depression.
迅速涌现的证据不断描述睡眠与情感脑功能之间密切的因果关系。长期的临床观察也印证了这些发现，表明几乎所有的情绪和焦虑障碍都与一种或多种睡眠异常同时出现。本综述旨在：(a) 综合近期的研究结果，描述睡眠引发的情感脑和行为益处，以及相反地，睡眠不足带来的有害损害；(b) 概述一个提议的框架，其中睡眠，特别是快速眼动 (REM) 睡眠，支持情感脑内稳态的过程，为机体次日的社交和情感功能做好最佳准备；(c) 描述这个假设的框架如何解释睡眠与精神障碍之间普遍存在的关系，特别关注创伤后应激障碍和重度抑郁症。
