Unite de Bioenergetique et Ingenierie des Proteines, Centre National de la Recherche Scientifique, Aix-Marseille Universite, 31 chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France,
J Biosci. 2014 Mar;39(1):13-27. doi: 10.1007/s12038-014-9414-3.
Biochemical information has been crucial for the development of evolutionary biology. On the one hand, the sequence information now appearing is producing a huge increase in the amount of data available for phylogenetic analysis; on the other hand, and perhaps more fundamentally, it allows understanding of the mechanisms that make evolution possible. Less well recognized, but just as important, understanding evolutionary biology is essential for understanding many details of biochemistry that would otherwise be mysterious, such as why the structures of NAD and other coenzymes are far more complicated than their functions would seem to require. Courses of biochemistry should thus pay attention to the essential role of evolution in selecting the molecules of life.
生物化学信息对于进化生物学的发展至关重要。一方面，现在出现的序列信息正在使可供系统发育分析使用的数据量大量增加；另一方面，也许更根本的是，它使人们能够理解使进化成为可能的机制。虽然不太为人所认识，但同样重要的是，理解进化生物学对于理解许多生物化学的细节也是必不可少的，否则这些细节将是神秘的，例如为什么 NAD 和其他辅酶的结构比它们的功能所要求的要复杂得多。因此，生物化学课程应该注意进化在选择生命分子方面的重要作用。
