Chandrashura（独行菜）的抗炎作用：一项实验研究
Anti-inflammatory effect of Chandrashura (Lepidium sativum Linn.) an experimental study.
作者信息
Raval Nita D, Ravishankar B, Ashok B K
机构信息
Lecturer, Department of Dravyaguna, Government Ayurvedic Collage, Junagadh, Gujarat, India.
Director, SDM Research Centre for Ayurveda and Allied Sciences, Kuthpady, Udupi, India.
出版信息
Ayu. 2013 Jul;34(3):302-4. doi: 10.4103/0974-8520.123132.
Lepidium sativum Linn. (Chandrashura) of Family Cruciferae (Brassicaceae) is being used by the people of Gujarat for treating inflammatory condition like arthritis. To evaluate its anti-inflammatory activity, Charles Foster albino rats were selected and experiments were carried out in three groups, therapeutic dose group, twice of therapeutic dose group and control group. In Carrageenan-induced paw oedema, the test drug produced moderate anti-inflammatory activity; however, the effect did not show statistically significant activity due to variation in the data of the control group. In formaldehyde-induced paw oedema in rats, the test drug produced moderate to significant suppression. This indicates that Chandrashura has a strong inhibitory effect on proliferation of fibroblasts and also probably has connective tissue modulation effect.
十字花科（芸苔科）的独行菜（Chandrashura），即药用独行菜，古吉拉特邦的人们用它来治疗诸如关节炎等炎症性疾病。为了评估其抗炎活性，选用了查尔斯·福斯特白化大鼠，并分为三组进行实验，即治疗剂量组、两倍治疗剂量组和对照组。在角叉菜胶诱导的爪肿胀实验中，受试药物产生了中度抗炎活性；然而，由于对照组数据的差异，该效应未显示出统计学上的显著活性。在甲醛诱导的大鼠爪肿胀实验中，受试药物产生了中度至显著的抑制作用。这表明Chandrashura对成纤维细胞的增殖具有强烈的抑制作用，并且可能还具有结缔组织调节作用。
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