V. N. Karazin Kharkiv National University, Kharkiv, Ukraine.
Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein 2028, South Africa.
Biomed Res Int. 2022 Jul 23;2022:3645038. doi: 10.1155/2022/3645038. eCollection 2022.
(garden cress) is a member of the Brassicaceae family that has been utilized for medicinal and culinary purposes in centuries. Anti-inflammatory, antioxidant, immunomodulatory, hepatoprotective, antihypertensive, antiasthmatic, and hypoglycemic properties are found in various portions of the plant. The anti-inflammatory, antioxidant, and immunomodulatory effects of L. sativum were the subject of this review.
The required information was gathered by searching the Web of Science, PubMed, and Scopus databases for the terms anti-inflammatory, antioxidant, immunomodulatory, immune system, and . Up until February 2022, the search was conducted.
TNF-, IL-6, IL-1, NO, iNOS, and HO-1 levels were reduced, indicating that has anti-inflammatory and immunomodulatory properties. Flavonoids, alkaloids, cyanogenic glycosides, tannins, glucosinolates, sterols, and triterpenes are the key chemical components that contribute to the anti-inflammatory effects. In peritoneal neutrophils, reduced oxidative stress by scavenging free radicals, as evidenced by a drop in superoxide anion and an increase in glutathione.
The anti-inflammatory, antioxidant, and immunomodulatory activities of could be explored in clinical trials to treat inflammatory and immune system illnesses.
（水芹）是十字花科的一员，几个世纪以来，它一直被用于药用和烹饪用途。该植物的不同部位具有抗炎、抗氧化、免疫调节、保肝、降压、抗哮喘和降血糖作用。本综述的主题是水芹的抗炎、抗氧化和免疫调节作用。
通过在 Web of Science、PubMed 和 Scopus 数据库中搜索“抗炎”、“抗氧化”、“免疫调节”、“免疫系统”和“”等术语，收集了所需信息。搜索截至 2022 年 2 月。
TNF-、IL-6、IL-1、NO、iNOS 和 HO-1 水平降低，表明水芹具有抗炎和免疫调节作用。黄酮类、生物碱、氰苷、单宁、硫代葡萄糖苷、甾醇和三萜类是具有抗炎作用的关键化学成分。在腹膜中性粒细胞中，通过清除自由基降低氧化应激，这表现为超氧阴离子减少和谷胱甘肽增加。
水芹的抗炎、抗氧化和免疫调节活性可以在临床试验中探索用于治疗炎症和免疫系统疾病。
