Jin Young Ju, Lee Sun Joo, Lee Won Yong, Jeong Woo-Jin, Ahn Soon-Hyun
Department of Otorhinolaryngology, Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 300 Gumi-dong, Bundang-gu, Seongnam, 463-707, Korea.
Eur Arch Otorhinolaryngol. 2014 Jul;271(7):1981-5. doi: 10.1007/s00405-014-2915-8. Epub 2014 Feb 8.
Although the frequent spontaneous resolution of contact granuloma is reported, the prognostic factor that can predict the possibility of resolution is not clear. We retrospectively analyzed the hospital records and laryngoscopic photos of 52 patients who were diagnosed with contact granuloma between May 2003 and June 2012. The reflux finding score and the shape of the granuloma were analyzed based on the initial laryngoscopy images; additionally, age, gender, chief complaint, and the side afflicted were also analyzed. Of the 52 patients, 40 who were treated conservatively were analyzed. Their mean age was 57.6 years and the mean follow-up period was 28.6 weeks. There was male predominance (87.5%), and the left side was more commonly afflicted (60.0%). Factors significantly associated with resolution included width/height ratio (P = 0.012) and gender (P = 0.048), but not reflux finding score (P = 0.713) or etiology (P = 0.382). So with this data, resolution of contact granuloma is highly probable in cases where the granuloma has a narrow base and the gender is female.
尽管有报道称接触性肉芽肿常常会自发消退,但能够预测其消退可能性的预后因素尚不清楚。我们回顾性分析了2003年5月至2012年6月期间被诊断为接触性肉芽肿的52例患者的医院记录和喉镜照片。基于初次喉镜检查图像分析反流发现评分和肉芽肿的形状;此外,还分析了年龄、性别、主要症状和受累侧别。在这52例患者中,对40例接受保守治疗的患者进行了分析。他们的平均年龄为57.6岁,平均随访期为28.6周。男性占优势(87.5%),左侧更常受累(60.0%)。与消退显著相关的因素包括宽高比(P = 0.012)和性别(P = 0.048),但不包括反流发现评分(P = 0.713)或病因(P = 0.382)。因此,根据这些数据,在肉芽肿基底狭窄且为女性的情况下,接触性肉芽肿极有可能消退。