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女性喉部接触性肉芽肿经皮糖皮质激素注射的短期疗效。

Short-term outcome of transcutaneous glucocorticoid injection for laryngeal contact granuloma in females.

机构信息

Department of Otolaryngology Head and Neck Surgery, Sixth Medical Center of PLA General Hospital; College of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China.

出版信息

Eur Arch Otorhinolaryngol. 2021 May;278(5):1499-1504. doi: 10.1007/s00405-020-06595-3. Epub 2021 Jan 13.

Abstract

OBJECTIVE

To evaluate the short-term efficacy of transcutaneous glucocorticoid injection for laryngeal contact granuloma in females.

METHODS

A total of 14 female patients with laryngeal contact granuloma treated in our outpatient department from November 2017 to January 2020 were included in the study. Inspiratory-phase laryngoscopy images were collected before treatment and 1 month after each injection, and the lesion size was measured and evaluated with ImageJ software.

RESULTS

Two patients achieved complete remission after one injection, with a percent reduction of 100%. After two injections, 4 patients achieved complete remission, with a percent reduction ranging from 96% to 100%. After 3 injections, 4 patients achieved complete remission (including one patient with bilateral lesions), and the percent reduction ranged from 95% to 100%. Three patients achieved incomplete remission, with a percent reduction of 46%, 55%, and 81%, respectively. In one case, there was no remission, and the granuloma increased in size after treatment.

CONCLUSION

In women with laryngeal contact granuloma, transcutaneous glucocorticoid injection therapy can quickly resolve the granuloma in a short period.

摘要

目的

评估经皮糖皮质激素注射治疗女性喉接触性肉芽肿的短期疗效。

方法

本研究纳入了 2017 年 11 月至 2020 年 1 月在我科门诊治疗的 14 例女性喉接触性肉芽肿患者。在治疗前和每次注射后 1 个月采集吸气相喉内窥镜图像,使用 ImageJ 软件测量并评估病变大小。

结果

2 例患者单次注射后完全缓解,缓解率为 100%。4 例患者接受 2 次注射后完全缓解,缓解率为 96%至 100%。4 例患者接受 3 次注射后完全缓解(包括 1 例双侧病变),缓解率为 95%至 100%。3 例患者未完全缓解,缓解率分别为 46%、55%和 81%。1 例患者无缓解,治疗后肉芽肿增大。

结论

在女性喉接触性肉芽肿患者中,经皮糖皮质激素注射治疗可在短期内迅速消退肉芽肿。

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