Akune Toru, Muraki Shigeyuki, Oka Hiroyuki, Tanaka Sakae, Kawaguchi Hiroshi, Tokimura Fumiaki, Yoshida Hideyo, Suzuki Takao, Nakamura Kozo, Yoshimura Noriko
Department of Clinical Motor System Medicine, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan,
J Orthop Sci. 2014 May;19(3):489-96. doi: 10.1007/s00776-014-0537-z. Epub 2014 Feb 8.
The present study aimed to investigate association of physical activities of daily living with the incidence of certified need of care in the national long-term care insurance (LTCI) system in elderly Japanese population-based cohorts.
Of the 3,040 participants in the baseline examination, we enrolled 1,773 (699 men, 1,074 women) aged 65 years or older who were not certified as in need of care-level elderly at baseline. Participants were followed during an average of 4.0 years for incident certification of need of care in the LTCI system. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used assess function. Associated factors in the baseline examination with the occurrence were determined by multivariate Cox proportional hazards regression analysis. Receiver operating characteristic curve analysis was performed to evaluate cut-off values for discriminating between the occurrence and the non-occurrence group.
All 17 items in the WOMAC function domain were significantly associated with the occurrence of certified need of care in the overall population. Cut-off values of the WOMAC function score that maximized the sum of sensitivity and specificity were around 4-6 in the overall population, in men, and in women. Multivariate Cox hazards regression analysis revealed that a WOMAC function score ≥4 was significantly associated with occurrence with the highest hazard ratio (HR) for occurrence after adjusting for confounders in the overall population (HR [95 % confidence interval (CI)] 2.54 [1.76-3.67]) and in women [HR (95 % CI) 3.13 (1.95-5.02)]. A WOMAC function score ≥5 was significantly associated with the highest HR for occurrence in men [HR (95 % CI) 1.88 (1.03-3.43)].
Physical dysfunction in daily living is a predictor of the occurrence of certified need of care. Elderly men with a WOMAC function score ≥5 and women with a score ≥4 should undergo early intervention programs to prevent subsequent deterioration.
本研究旨在调查日本老年人群队列中,日常生活身体活动与国家长期护理保险(LTCI)系统中认证护理需求发生率之间的关联。
在基线检查的3040名参与者中,我们纳入了1773名(699名男性,1074名女性)65岁及以上、基线时未被认证为需要护理级别的老年人。参与者平均随访4.0年,以观察LTCI系统中护理需求的事件认证情况。使用西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评估功能。通过多变量Cox比例风险回归分析确定基线检查中与发生情况相关的因素。进行受试者工作特征曲线分析,以评估区分发生组和未发生组的临界值。
WOMAC功能领域的所有17项指标均与总体人群中认证护理需求的发生显著相关。在总体人群、男性和女性中,使敏感性和特异性之和最大化的WOMAC功能评分临界值约为4-6。多变量Cox风险回归分析显示,在总体人群(风险比[95%置信区间(CI)]2.54[1.76-3.67])和女性[风险比(95%CI)3.13(1.95-5.02)]中,调整混杂因素后,WOMAC功能评分≥4与发生情况显著相关,发生风险比最高。WOMAC功能评分≥5与男性发生风险比最高显著相关[风险比(95%CI)1.88(1.03-3.43)]。
日常生活中的身体功能障碍是认证护理需求发生的预测因素。WOMAC功能评分≥5的老年男性和评分≥4的老年女性应接受早期干预计划,以防止随后的病情恶化。