Sattayut S, Bradley P
Lasers in Dentistry Research Group, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand.
Oral Diagnostic Sciences, College of Dental Medicine, Nova Southeastern University, Ft. Lauderdale, Florida, USA.
Laser Ther. 2012 Sep 30;21(3):183-92. doi: 10.5978/islsm.12-OR-09. Epub 2012 Aug 13.
A double-blind clinical trial was conducted on 30 female Temporomandibular Disorders (TMD) patients who had pain as a chief complaint. The patients were randomly allocated into three groups based on Low Intensity Laser (LILT) regimes namely 820 nm Gallium Aluminium Arsenide (GaAlAs) laser at energy densities of 21.4J/cm(2), 107 J/cm(2) and placebo laser. Each patient had three LILT treatments in a week. The pressure pain threshold (PPT) of trigger points in masticatory muscles, unassisted maximum mouth opening without pain (MOSP) and symptom severity index (SSI) were recorded as baseline data and monitored after every treatment. Jaw kinesiology, electromyography (EMG) and pain rating index from McGill pain questionnaire were also recorded as baseline and final results. The analysis of covariance and further analysis showed that the higher energy density laser group had significant increases in PPT and EMG amplitude recorded from voluntary clenching (cEMG) compared with the placebo group at P values 0.0001 and 0.022 respectively. A significantly greater number of patients recovered from myofascial pain and TMJ arthralgia as assessed clinically in the higher energy group compared with the placebo (P value = 0.02 and 0.006 respectively). There was no statistically significant difference in the other parameters of assessment among the groups at a P value 0.05. At a period of 2 to 4 weeks review after LILT, there was an average 52% reduction of pain as assessed by SSI.
对30名以疼痛为主要症状的女性颞下颌关节紊乱病(TMD)患者进行了一项双盲临床试验。根据低强度激光(LILT)方案,将患者随机分为三组,即能量密度为21.4J/cm²、107J/cm²的820nm砷化镓铝(GaAlAs)激光组和安慰剂激光组。每位患者每周接受三次LILT治疗。记录咀嚼肌触发点的压痛阈值(PPT)、无痛时的最大自主开口度(MOSP)和症状严重程度指数(SSI)作为基线数据,并在每次治疗后进行监测。还记录了下颌运动学、肌电图(EMG)以及麦吉尔疼痛问卷的疼痛评分指数作为基线和最终结果。协方差分析及进一步分析表明,与安慰剂组相比,高能量密度激光组的PPT和自愿紧咬时记录的EMG振幅(cEMG)有显著增加,P值分别为0.0001和0.022。与安慰剂组相比,高能量组经临床评估有显著更多的患者从肌筋膜疼痛和颞下颌关节痛中康复(P值分别为0.02和0.006)。在P值为0.05时,各组间其他评估参数无统计学显著差异。在LILT治疗后2至4周的复查期,根据SSI评估,疼痛平均减轻了52%。