Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS , 91198 Gif-sur-Yvette Cedex, France.
Org Lett. 2014 Feb 21;16(4):1240-3. doi: 10.1021/ol500374e. Epub 2014 Feb 12.
A photoredox-catalzyed trifluoromethylation of enecarbamates process is reported. This pathway uses Togni's reagent as the CF3 source and follows a radical/cationic pathway. Under the optimized conditions using [Ru(bpy)3(PF6)2] as the photocatalyst, a wide range of substituted enecarbamates can readily be difunctionalized by means of various O, N, and C nucleophiles.
本文报道了一种光氧化还原催化的烯基氨基甲酸酯三氟甲基化反应。该反应以 Togni 试剂作为 CF3 源，通过自由基/阳离子历程进行。在优化条件下，以[Ru(bpy)3(PF6)2]作为光催化剂，各种 O、N 和 C 亲核试剂可以很容易地对取代的烯基氨基甲酸酯进行双官能化。
