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Reliable change in depression during behavioral weight loss treatment among women with major depression.女性重度抑郁症患者在行为减肥治疗过程中抑郁的可靠变化。
Obesity (Silver Spring). 2013 Mar;21(3):E211-8. doi: 10.1002/oby.20113.
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Randomized controlled trial of behavioral treatment for comorbid obesity and depression in women: the Be Active Trial.随机对照试验研究行为治疗对女性肥胖合并抑郁共病的疗效:Be Active 试验。
Int J Obes (Lond). 2013 Nov;37(11):1427-34. doi: 10.1038/ijo.2013.25. Epub 2013 Mar 5.
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Stage of change and motivation to healthier lifestyle in non-alcoholic fatty liver disease.非酒精性脂肪性肝病的改变阶段和更健康生活方式的动机。
J Hepatol. 2013 Apr;58(4):771-7. doi: 10.1016/j.jhep.2012.11.031. Epub 2012 Nov 29.
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Depression severity, diet quality, and physical activity in women with obesity and depression.肥胖合并抑郁女性的抑郁严重程度、饮食质量与身体活动。
J Acad Nutr Diet. 2012 May;112(5):693-8. doi: 10.1016/j.jand.2012.02.006. Epub 2012 Apr 25.
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The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association.非酒精性脂肪性肝病的诊断与管理:美国肝病研究协会、美国胃肠病学会和美国胃肠病协会实践指南
Hepatology. 2012 Jun;55(6):2005-23. doi: 10.1002/hep.25762.
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Cognitive function predicts weight loss after bariatric surgery.认知功能可预测减重手术后的体重减轻情况。
Surg Obes Relat Dis. 2013 May-Jun;9(3):453-9. doi: 10.1016/j.soard.2011.10.008. Epub 2011 Oct 29.
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Associations of mood and anxiety disorders with obesity: comparisons by ethnicity.心境和焦虑障碍与肥胖的关联:按种族的比较。
J Psychosom Res. 2011 Nov;71(5):319-24. doi: 10.1016/j.jpsychores.2011.03.004. Epub 2011 Apr 22.
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A review of the association between obesity and cognitive function across the lifespan: implications for novel approaches to prevention and treatment.肥胖与全生命周期认知功能之间关联的综述:对预防和治疗新方法的启示
Obes Rev. 2011 Sep;12(9):740-55. doi: 10.1111/j.1467-789X.2011.00920.x.
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The psychology of patient compliance: a focused review of the literature.患者依从性的心理学研究:文献综述
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非酒精性脂肪性肝病行为改变的准备情况:对多学科护理模式的影响。

Readiness for behaviour change in non-alcoholic fatty liver disease: implications for multidisciplinary care models.

作者信息

Stewart Karen E, Haller Deborah L, Sargeant Carol, Levenson James L, Puri Puneet, Sanyal Arun J

机构信息

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

出版信息

Liver Int. 2015 Mar;35(3):936-43. doi: 10.1111/liv.12483. Epub 2014 Mar 10.

DOI:10.1111/liv.12483
PMID:24521540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4266620/
Abstract

BACKGROUND & AIMS: Weight management is a cornerstone of treatment for overweight/obese persons with non-alcoholic fatty liver disease (NAFLD). This exploratory study sought to: (i) evaluate readiness to change weight-related behaviours; (ii) assess psychosocial characteristics that may interfere with weight loss; and (iii) evaluate how baseline psychosocial features associate with 6-month change in weight in persons with NAFLD receiving standard medical care. The purpose of this investigation was to develop hypotheses regarding relationships between psychosocial factors and weight for use in future fully powered studies and clinical interventions

METHODS

Fifty-eight overweight/obese participants with NAFLD completed baseline measures of personality, psychiatric symptoms and readiness for behaviour change and were followed up for 6 months in standard care.

RESULTS

One-third of participants (31.0%) were not interested in making weight-related behaviour changes; 58.6% were considering making a change, and 10.4% of individuals were actively working on or preparing to change. Six-month change in weight was non-significant and was not associated with baseline readiness for change. Depression, low conscientiousness and high neuroticism were associated with higher weight at 6-month follow-up with small to large effect sizes.

CONCLUSIONS

Although participants received nutritional education and guidance, very few individuals presented in the active stage of change. Although readiness for change did not predict subsequent change in weight, personality factors and psychiatric symptoms were associated with weight outcomes. Integrated multidisciplinary approaches that address psychiatric needs and provide behavioural support for weight loss may help patients with NAFLD implement sustained lifestyle changes.

摘要

背景与目的

体重管理是超重/肥胖的非酒精性脂肪性肝病(NAFLD)患者治疗的基石。这项探索性研究旨在:(i)评估改变与体重相关行为的意愿;(ii)评估可能干扰体重减轻的心理社会特征;(iii)评估在接受标准医疗护理的NAFLD患者中,基线心理社会特征与6个月体重变化之间的关联。本调查的目的是就心理社会因素与体重之间的关系提出假设,以供未来进行充分有力的研究和临床干预时使用。

方法

58名超重/肥胖的NAFLD参与者完成了人格、精神症状和行为改变意愿的基线测量,并在标准护理下随访6个月。

结果

三分之一的参与者(31.0%)对改变与体重相关的行为不感兴趣;58.6%的人在考虑做出改变,10.4%的人正在积极努力或准备改变。6个月时体重变化不显著,且与基线改变意愿无关。抑郁、低尽责性和高神经质与6个月随访时较高的体重相关,效应大小从小到中。

结论

尽管参与者接受了营养教育和指导,但很少有人处于积极改变阶段。尽管改变意愿并不能预测随后的体重变化,但人格因素和精神症状与体重结果相关。综合多学科方法,解决精神需求并为体重减轻提供行为支持,可能有助于NAFLD患者实现持续的生活方式改变。