Kosmalski Marcin, Frankowski Rafał, Różycka-Kosmalska Monika, Sipowicz Kasper, Pietras Tadeusz, Mokros Łukasz
Department of Clinical Pharmacology, Medical University of Lodz, 90-153 Lodz, Poland.
Students' Research Club, Department of Clinical Pharmacology, Medical University of Lodz, 90-153 Lodz, Poland.
J Clin Med. 2023 Jul 3;12(13):4468. doi: 10.3390/jcm12134468.
The increasing prevalence of type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD) states a serious problem for public health. The introduction of effective methods of treatment and prevention is crucial to avoid complications of these diseases. Among them, we can specify psychological factors that affect everyday life and determine the patient's attitude towards therapy, and what follows, their compliance in treatment. The literature indicates these connections in various ways; in our study, we extend this view to include a broader perspective of human personality.
We decided to investigate the associations between personality factors and metabolic parameters in patients with NAFLD and T2DM in order to better understand the patient's approach to the treatment of a chronic disease, such as those mentioned, and to establish the basis for further research implementing psychological interventions in the treatment of NAFLD and T2DM.
One hundred participants with NAFLD and T2DM underwent blood tests and anthropometric measures. Each of them was asked to complete five questionnaires evaluating their personality properties.
We revealed that a rise in body mass index is related to a fall in the emotional intelligence factor of utilizing emotions, and a rise in emotional perception. The decrease in task-oriented coping style and a rise in emotion-oriented coping style are associated with a waist-hip ratio increase. The increase in fasting plasma glucose is predicted by a decrease in task-oriented coping style score. A fall in social diversion coping style score is associated with a high-density lipoprotein increase; in turn, a triglycerides increase is connected with a decline in rhythmicity score.
The personality factors are in relationship in the management of NAFLD and T2DM. They affect a patient's approach to treatment, which is very important, because we know lifestyle and dietary interventions are an important part of the treatment of these diseases. The compliance manifests by lifestyle modifications, taking medications regularly, measuring blood glucose, and inspection visits in outpatients' clinics are a large part of a diabetic's life. Future studies introducing psychological intervention to improve, e.g., coping styles or rhythmicity are needed to implement new methods of patient management.
2型糖尿病（T2DM）和非酒精性脂肪性肝病（NAFLD）的患病率不断上升，给公共卫生带来了严重问题。引入有效的治疗和预防方法对于避免这些疾病的并发症至关重要。其中，我们可以明确影响日常生活的心理因素，并确定患者对治疗的态度，以及随之而来的治疗依从性。文献以各种方式表明了这些联系；在我们的研究中，我们将这一观点扩展到包括更广泛的人格视角。
我们决定研究NAFLD和T2DM患者人格因素与代谢参数之间的关联，以便更好地理解患者对上述慢性病治疗的态度，并为在NAFLD和T2DM治疗中实施心理干预的进一步研究奠定基础。
100名NAFLD和T2DM患者接受了血液检查和人体测量。他们每人被要求完成五份评估其人格特质的问卷。
我们发现体重指数的升高与利用情绪的情商因素下降以及情绪感知的升高有关。任务导向型应对方式的减少和情绪导向型应对方式的增加与腰臀比的增加有关。空腹血糖的升高可通过任务导向型应对方式得分的降低来预测。社交转移应对方式得分的下降与高密度脂蛋白的升高有关；反过来，甘油三酯的升高与节律性得分的下降有关。
人格因素在NAFLD和T2DM的管理中存在关联。它们影响患者的治疗态度，这非常重要，因为我们知道生活方式和饮食干预是这些疾病治疗的重要组成部分。通过改变生活方式、定期服药、测量血糖以及在门诊就诊来表现的依从性是糖尿病患者生活的很大一部分。未来需要开展引入心理干预以改善应对方式或节律性等的研究，以实施新的患者管理方法。
