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[抗磷脂综合征相关的Libman-Sacks心内膜炎。1例报告]

[Libman-Sacks endocarditis associated with antiphospholipid syndrome. Report of one case].

作者信息

González Alejandro, Vergara Maximiliano, Heredia Ana, Llanos Leonidas, Araos Fernando

出版信息

Rev Med Chil. 2013 Sep;141(9):1206-10. doi: 10.4067/S0034-98872013000900015.

Abstract

Libman-Sacks endocarditis is a non-infectious valvular damage associated with autoimmune disorders such as Systemic Lupus Erythematosus and Antiphospholipid Syndrome. We report a 17-year-old female consulting in the emergency room due to a right hemiparesis and aphasia. A magnetic resonance imaging showed multiple infarctions in the territory of the left middle cerebral artery, presumably of embolic origin. A trans-esophageal echocardiogram showed a vegetation in the mitral valve. Blood cultures were negative. Antinuclear antibodies and serological tests for antiphospholipid syndrome were positive. Oral anticoagulation was started and the patient was discharged. After six months of follow up, antiphospholipid antibodies are still positive.

摘要

利布曼-萨克斯心内膜炎是一种与自身免疫性疾病(如系统性红斑狼疮和抗磷脂综合征)相关的非感染性瓣膜损害。我们报告一名17岁女性因右侧偏瘫和失语在急诊室就诊。磁共振成像显示左侧大脑中动脉供血区域有多处梗死,推测为栓子来源。经食管超声心动图显示二尖瓣有赘生物。血培养为阴性。抗核抗体及抗磷脂综合征血清学检查呈阳性。开始口服抗凝治疗,患者出院。随访6个月后,抗磷脂抗体仍为阳性。

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