Tusor Nora, Arichi Tomoki, Counsell Serena J, Edwards A David
Centre for the Developing Brain, Department of Perinatal Imaging, St Thomas' Hospital, King's College London, Westminster Bridge Road, London SE1 7EH, UK.
Centre for the Developing Brain, Department of Perinatal Imaging, St Thomas' Hospital, King's College London, Westminster Bridge Road, London SE1 7EH, UK; Department of Bioengineering, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Clin Perinatol. 2014 Mar;41(1):25-45. doi: 10.1016/j.clp.2013.10.001. Epub 2013 Dec 12.
Infants who are born preterm have a high incidence of neurocognitive and neurobehavioral abnormalities, which may be associated with impaired brain development. Advanced magnetic resonance imaging (MRI) approaches, such as diffusion MRI (d-MRI) and functional MRI (fMRI), provide objective and reproducible measures of brain development. Indices derived from d-MRI can be used to provide quantitative measures of preterm brain injury. Although fMRI of the neonatal brain is currently a research tool, future studies combining d-MRI and fMRI have the potential to assess the structural and functional properties of the developing brain and its response to injury.
早产出生的婴儿神经认知和神经行为异常的发生率很高，这可能与大脑发育受损有关。先进的磁共振成像（MRI）方法，如扩散MRI（d-MRI）和功能MRI（fMRI），可提供大脑发育的客观且可重复的测量指标。从d-MRI得出的指标可用于提供早产脑损伤的定量测量。虽然新生儿脑功能磁共振成像目前是一种研究工具，但未来结合d-MRI和fMRI的研究有可能评估发育中大脑的结构和功能特性及其对损伤的反应。
