Bartley Emily J, Edmond Sara N, Wren Anava A, Somers Tamara J, Teo Irene, Zhou Sicong, Rowe Krista A, Abernethy Amy P, Keefe Francis J, Shelby Rebecca A
Pain Research and Intervention Center of Excellence, University of Florida College of Dentistry, Gainesville, Florida, USA.
Duke University Medical Center, Durham, North Carolina, USA.
J Pain Symptom Manage. 2014 Sep;48(3):374-84. doi: 10.1016/j.jpainsymman.2013.09.019. Epub 2014 Feb 13.
Holding back, or withholding discussion of disease-related thoughts and emotions, is associated with negative outcomes including lower quality of life, diminished well-being, and relational distress. For patients undergoing hematopoietic stem cell transplantation (HSCT), the degree to which one holds back from discussing illness-related concerns may be an important determinant of social well-being and health; however, this has not been systematically assessed in this population.
The purpose of the present study was to assess the moderating effects of holding back discussion of disease-related concerns on the relationship between health-related symptoms and social well-being in adult patients undergoing HSCT.
Seventy autologous (n = 55) and allogeneic (n = 15) HSCT patients completed measures of holding back, social well-being, and health symptoms (i.e., pain, fatigue, sleep problems, cognitive problems) both before and after transplantation (i.e., three months after transplantation and six months after transplantation).
In patients with average to high levels of holding back, health symptoms were significantly related to lower levels of social well-being; however, for patients with low levels of holding back, the relationship between health symptoms and social well-being was not significant.
The results of the present study suggest that the level of holding back may be important in understanding how health-related symptoms relate to social well-being in patients undergoing HSCT. These findings underscore the importance of addressing how patients undergoing HSCT communicate about their disease with others as this may be related to their adjustment to illness and treatment.
抑制或隐瞒与疾病相关的想法和情绪，会带来包括生活质量下降、幸福感降低和关系困扰等负面结果。对于接受造血干细胞移植（HSCT）的患者而言，抑制讨论疾病相关担忧的程度，可能是其社会幸福感和健康状况的重要决定因素；然而，这一点在该人群中尚未得到系统评估。
本研究旨在评估抑制讨论疾病相关担忧对接受HSCT的成年患者健康相关症状与社会幸福感之间关系的调节作用。
70名自体（n = 55）和异体（n = 15）HSCT患者在移植前后（即移植后三个月和移植后六个月）完成了关于抑制程度、社会幸福感和健康症状（即疼痛、疲劳、睡眠问题、认知问题）的测量。
在抑制程度处于平均水平至高水平的患者中，健康症状与较低的社会幸福感显著相关；然而，对于抑制程度较低的患者，健康症状与社会幸福感之间的关系并不显著。
本研究结果表明，抑制程度在理解接受HSCT患者的健康相关症状与社会幸福感之间的关系方面可能很重要。这些发现强调了解决接受HSCT患者如何与他人交流其疾病情况的重要性，因为这可能与他们对疾病和治疗的适应有关。
