Institute of Biophysics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; Jožef Stefan Institute, Ljubljana, Slovenia.
Institute of Biophysics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; University of Nova Gorica, Nova Gorica, Slovenia.
Adv Colloid Interface Sci. 2014 Jun;208:189-96. doi: 10.1016/j.cis.2014.01.010. Epub 2014 Jan 24.
About forty years ago it was realized that phospholipid membranes, because they are composed of two layers, exhibit particular, and specific mechanical properties. This led to the concept of nonlocal membrane bending, often called area difference elasticity. We present a short history of the development of the concept, followed by arguments for a proper definition of the corresponding elastic constant. The effects of the nonlocal bending energy on vesicle shape are explained. It is demonstrated that lipid vesicles, cells and cellular aggregates exhibit phenomena that can only be described in a complete manner by considering nonlocal bending.
大约四十年前，人们意识到磷脂双分子层由于由两层组成，具有特殊的、特定的力学性质。这导致了非局部膜弯曲的概念的产生，通常称为面积差弹性。我们介绍了该概念的发展简史，然后提出了相应弹性常数的合理定义的论据。解释了非局部弯曲能对囊泡形状的影响。证明了只有通过考虑非局部弯曲，才能完整地描述脂质囊泡、细胞和细胞聚集体所表现出的现象。
